TY - CHAP
T1 - Estrogens and gonadal function in schizophrenia and related psychoses
AU - Riecher-Rossler, Anita
AU - Kulkarni, Jayashri
PY - 2011
Y1 - 2011
N2 - Recent research has increasingly pointed to the importance of estrogens and the hypothalamic-pituitary-gonadal axis in schizophrenia. Specifically, there is mounting evidence from clinical, epidemiological, and basic research that estradiol, the main component of estrogens, exerts protective effects in schizophrenia and related psychoses. Possible modes of action of this hormone in the brain have been suggested, and clinical intervention studies have reported the first positive results. Furthermore, there are an increasing number of reports on gonadal dysfunction and states of estrogen deficiency in women with schizophrenia. These findings could have important implications for clinicians and researchers alike. ? Springer-Verlag Berlin Heidelberg 2011.
AB - Recent research has increasingly pointed to the importance of estrogens and the hypothalamic-pituitary-gonadal axis in schizophrenia. Specifically, there is mounting evidence from clinical, epidemiological, and basic research that estradiol, the main component of estrogens, exerts protective effects in schizophrenia and related psychoses. Possible modes of action of this hormone in the brain have been suggested, and clinical intervention studies have reported the first positive results. Furthermore, there are an increasing number of reports on gonadal dysfunction and states of estrogen deficiency in women with schizophrenia. These findings could have important implications for clinicians and researchers alike. ? Springer-Verlag Berlin Heidelberg 2011.
U2 - 10.1007/7854_2010_100
DO - 10.1007/7854_2010_100
M3 - Chapter (Book)
SN - 9783642200052
T3 - Current Topics in Behavioral Neurosciences
SP - 155
EP - 171
BT - Biological Basis of Sex Differences in Psychopharmacology
A2 - Neill, Jo C.
A2 - Kulkarni, Jayashri
PB - Springer
CY - Germany
ER -