Establishing functional residual capacity at birth: The effect of sustained inflation and positive end-expiratory pressure in a preterm rabbit model

Arjan B Te Pas, Melissa Li-Lian Siew, Megan Jane Wallace, Marcus John Kitchen, Andreas Fouras, Robert A Lewis, Naoto Yagi, Kentaro Uesugi, Susan Donath, Peter G Davis, Colin J Morley, Stuart Brian Hooper

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)

Abstract

The effect of inflation length on lung aeration pattern, tidal volumes and functional residual capacity (FRC) immediately after birth was investigated. Preterm rabbits (28 days), randomized into 4 groups, received a 1, 5, 10, or 20 sec inflation (SI) followed by ventilation with 5 cmH2O end-expiratory pressure. Gas volumes were measured by plethysmography and uniformity of lung aeration by phase contrast X-ray imaging for 7 minutes. The first inspiratory volume significantly (p
Original languageEnglish
Pages (from-to)537 - 541
Number of pages5
JournalPediatric Research
Volume65
Issue number5
DOIs
Publication statusPublished - 2009

Cite this

Te Pas, Arjan B ; Siew, Melissa Li-Lian ; Wallace, Megan Jane ; Kitchen, Marcus John ; Fouras, Andreas ; Lewis, Robert A ; Yagi, Naoto ; Uesugi, Kentaro ; Donath, Susan ; Davis, Peter G ; Morley, Colin J ; Hooper, Stuart Brian. / Establishing functional residual capacity at birth: The effect of sustained inflation and positive end-expiratory pressure in a preterm rabbit model. In: Pediatric Research. 2009 ; Vol. 65, No. 5. pp. 537 - 541.
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Establishing functional residual capacity at birth: The effect of sustained inflation and positive end-expiratory pressure in a preterm rabbit model. / Te Pas, Arjan B; Siew, Melissa Li-Lian; Wallace, Megan Jane; Kitchen, Marcus John; Fouras, Andreas; Lewis, Robert A; Yagi, Naoto; Uesugi, Kentaro; Donath, Susan; Davis, Peter G; Morley, Colin J; Hooper, Stuart Brian.

In: Pediatric Research, Vol. 65, No. 5, 2009, p. 537 - 541.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Siew, Melissa Li-Lian

AU - Wallace, Megan Jane

AU - Kitchen, Marcus John

AU - Fouras, Andreas

AU - Lewis, Robert A

AU - Yagi, Naoto

AU - Uesugi, Kentaro

AU - Donath, Susan

AU - Davis, Peter G

AU - Morley, Colin J

AU - Hooper, Stuart Brian

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