Essential oil composition and in vitro antioxidant activity of ethanolic extract of Thymus daenensis celak from iran

Zahra Sabahi, Zarshenas M. Mohammad, Fatemeh Farmani, Pouya Faridi, Soheila Moein, Mahmood Reza Moein

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Abstract

The genus Thymus (Lamiaceae) family possesses different species in Iran. In this study, the antioxidant potential of essential oil and crude extract of one of the endemic species of Thymus, Thymus daenensis were evaluated. For analysis antioxidant potency, nitric oxide, DPPH free radical, hydroxyl radical scavenging, ferric reducing antioxidant power assay and inhibition of lipid peroxidation were used. The antioxidant potential of crude extract by DPPH free radical scavenging (IC50 = 194 ± 0.02 μg/mL), nitric oxide scavenging (74±0.0 %) and hydroxyl radical scavenging (60.2 ± 0.27 %) was more active than essential oil. In nitric oxide scavenging crude extract was more active than the antioxidant standard BHT, 42±0.79. Inhibition of lipid peroxidation of essential oil and crude extract of Thymus daenensis were lower than BHT and Vit C. The essential oil of Thymus daenensis showed no antioxidant potency by ferric-reducing antioxidant power (Frap) assay but the extract possesses antioxidant activity (10.16± 1.6 μmol/g) by this method. The profile of essential oil was detected by GC-mass. The main component of essential oil was Geraniol (66.8%), Geranyl acetate (13.9%) and Beta caryophyllene (9.6%).

Original languageEnglish
Pages (from-to)153-158
Number of pages6
JournalGlobal Journal of Pharmacology
Volume7
Issue number2
DOIs
Publication statusPublished - 2013
Externally publishedYes

Keywords

  • Antioxidant potential
  • Crude extract
  • Essential oil
  • GC-mass
  • Thymus daenensis

Cite this