Escherichia coli harboring mcr-1 in a cluster of liver transplant recipients: Detection through active surveillance and whole-genome sequencing

Nenad Macesic, Sabrina Khan, Marla J. Giddins, Daniel E. Freedberg, Susan Whittier, Daniel A. Green, E. Yoko Furuya, Elizabeth C. Verna, Medini K. Annavajhala, Angela Gomez-Simmonds, Anne Catrin Uhlemann

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3 Citations (Scopus)

Abstract

mcr-1, a plasmid-associated gene for colistin resistance, was first described in China in 2015, but its spread in the United States is unknown. We report detection of mcr-1-carrying Escherichia coli ST117 in a cluster of three liver transplant recipients.

Original languageEnglish
Article numbere02680-18
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume63
Issue number6
DOIs
Publication statusPublished - Jun 2019

Keywords

  • Antimicrobial resistance
  • Colistin
  • Mcr-1
  • Polymyxin B
  • Whole-genome sequencing

Cite this

Macesic, N., Khan, S., Giddins, M. J., Freedberg, D. E., Whittier, S., Green, D. A., Furuya, E. Y., Verna, E. C., Annavajhala, M. K., Gomez-Simmonds, A., & Uhlemann, A. C. (2019). Escherichia coli harboring mcr-1 in a cluster of liver transplant recipients: Detection through active surveillance and whole-genome sequencing. Antimicrobial Agents and Chemotherapy, 63(6), [e02680-18]. https://doi.org/10.1128/AAC.02680-18