Abstract
S4 Fig. IFNα and IFNγ transcription levels are not altered by MAVS or SARS-CoV-2 genes. HEK-293T cells were transfected with MAVS and a SARS-CoV-2 viral gene (or control). 24 hours post transfection transcript levels were analyzed by qPCR for expression of IFNα2, IFNα4, IFNα6, IFNα10 and IFNγ. The data presented are expression levels normalized to the housekeeping gene HPRT1 (ΔCT). Data presented are means of 2–4 independent experiments and their standard error. (TIF)
| Original language | English |
|---|---|
| Article number | e1010146 |
| Number of pages | 1 |
| Journal | PLoS Pathogens |
| Volume | 17 |
| Issue number | 12 |
| DOIs |
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| Publication status | Published - Dec 2021 |
Research output
- 8 Citations
- 1 Article
-
SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon
Shemesh, M., Aktepe, T. E., Deerain, J. M., McAuley, J. L., Audsley, M. D., David, C. T., Purcell, D. F. J., Urin, V., Hartmann, R., Moseley, G. W., Mackenzie, J. M., Schreiber, G. & Harari, D., Aug 2021, In: PLoS Pathogens. 17, 8, 31 p., e1009800.Research output: Contribution to journal › Article › Research › peer-review
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