Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056

Sebastien Jacquemont; Aurore Curie; Vincent des Portes; Maria Torrioli; Elizabeth Berry-Kravis; Randi Hagerman; Feliciano Ramos; Kim Cornish; Yunsheng He; Charles Paulding; Giovanni Neri; Fei Chen; Nouchine Hadjikhani; Danielle Martinet; Joanne Meyer; Jacques Beckmann; Karine Delange; Amandine Brun; Gerald Bussy; Fabrizio Gasparini; Talita Hilse; Annette Floesser; Janice Branson; Graeme Bilbe; Donald Johns; Baltazar Gomez-Mancilla

doi:10.1126/scitranslmed.3001708

Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056

Sebastien Jacquemont, Aurore Curie, Vincent des Portes, Maria Torrioli, Elizabeth Berry-Kravis, Randi Hagerman, Feliciano Ramos, Kim Cornish, Yunsheng He, Charles Paulding, Giovanni Neri, Fei Chen, Nouchine Hadjikhani, Danielle Martinet, Joanne Meyer, Jacques Beckmann, Karine Delange, Amandine Brun, Gerald Bussy, Fabrizio GaspariniTalita Hilse, Annette Floesser, Janice Branson, Graeme Bilbe, Donald Johns, Baltazar Gomez-Mancilla

School of Psychological Sciences

Research output: Contribution to journal › Article › Research › peer-review

333 Citations (Scopus)

Original language	English
Article number	64ra1
Number of pages	9
Journal	Science Translational Medicine
Volume	3
Issue number	64
DOIs	https://doi.org/10.1126/scitranslmed.3001708
Publication status	Published - 2011

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Jacquemont, S., Curie, A., des Portes, V., Torrioli, M., Berry-Kravis, E., Hagerman, R., Ramos, F., Cornish, K., He, Y., Paulding, C., Neri, G., Chen, F., Hadjikhani, N., Martinet, D., Meyer, J., Beckmann, J., Delange, K., Brun, A., Bussy, G., ... Gomez-Mancilla, B. (2011). Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056. Science Translational Medicine, 3(64), Article 64ra1. https://doi.org/10.1126/scitranslmed.3001708

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title = "Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056",

author = "Sebastien Jacquemont and Aurore Curie and \{des Portes\}, Vincent and Maria Torrioli and Elizabeth Berry-Kravis and Randi Hagerman and Feliciano Ramos and Kim Cornish and Yunsheng He and Charles Paulding and Giovanni Neri and Fei Chen and Nouchine Hadjikhani and Danielle Martinet and Joanne Meyer and Jacques Beckmann and Karine Delange and Amandine Brun and Gerald Bussy and Fabrizio Gasparini and Talita Hilse and Annette Floesser and Janice Branson and Graeme Bilbe and Donald Johns and Baltazar Gomez-Mancilla",

year = "2011",

doi = "10.1126/scitranslmed.3001708",

language = "English",

volume = "3",

journal = "Science Translational Medicine",

issn = "1946-6234",

publisher = "American Association for the Advancement of Science (AAAS)",

number = "64",

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Jacquemont, S, Curie, A, des Portes, V, Torrioli, M, Berry-Kravis, E, Hagerman, R, Ramos, F, Cornish, K, He, Y, Paulding, C, Neri, G, Chen, F, Hadjikhani, N, Martinet, D, Meyer, J, Beckmann, J, Delange, K, Brun, A, Bussy, G, Gasparini, F, Hilse, T, Floesser, A, Branson, J, Bilbe, G, Johns, D & Gomez-Mancilla, B 2011, 'Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056', Science Translational Medicine, vol. 3, no. 64, 64ra1. https://doi.org/10.1126/scitranslmed.3001708

TY - JOUR

T1 - Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056

AU - Jacquemont, Sebastien

AU - Curie, Aurore

AU - des Portes, Vincent

AU - Torrioli, Maria

AU - Berry-Kravis, Elizabeth

AU - Hagerman, Randi

AU - Ramos, Feliciano

AU - Cornish, Kim

AU - He, Yunsheng

AU - Paulding, Charles

AU - Neri, Giovanni

AU - Chen, Fei

AU - Hadjikhani, Nouchine

AU - Martinet, Danielle

AU - Meyer, Joanne

AU - Beckmann, Jacques

AU - Delange, Karine

AU - Brun, Amandine

AU - Bussy, Gerald

AU - Gasparini, Fabrizio

AU - Hilse, Talita

AU - Floesser, Annette

AU - Branson, Janice

AU - Bilbe, Graeme

AU - Johns, Donald

AU - Gomez-Mancilla, Baltazar

PY - 2011

Y1 - 2011

UR - https://www.scopus.com/pages/publications/78650937072

U2 - 10.1126/scitranslmed.3001708

DO - 10.1126/scitranslmed.3001708

M3 - Article

SN - 1946-6234

VL - 3

JO - Science Translational Medicine

JF - Science Translational Medicine

IS - 64

M1 - 64ra1

ER -

Epigenetic modification of the FMR1 gene in Fragile X Syndrome is associated with differential response to the mGluR5 antagonist AFQ056

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