Epidemic typhoid in Vietnam: Molecular typing of multiple-antibiotic- resistant Salmonella enterica serotype typhi from four outbreaks

Phillippa Connerton, John Wain, Tran T. Hien, Tahir Ali, Christopher Parry, Nguyen T. Chinh, Ha Vinh, Vo A. Ho, To S. Diep, Nicholas P.J. Day, Nicholas J. White, Gordon Dougan, Jeremy J. Farrar

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Abstract

Multidrug-resistant Salmonella enterica serotype Typhi isolates from four outbreaks of typhoid fever in southern Vietnam between 1993 and 1997 were compared. Pulsed-field gel electrophoresis, bacteriophage and plasmid typing, and antibiotic susceptibilities showed that independent outbreaks of multidrug-resistant typhoid fever in southern Vietnam are caused by single bacterial strains. However, different outbreaks do not derive from the clonal expansion of a single multidrug-resistant serotype Typhi strain.

Original languageEnglish
Pages (from-to)895-897
Number of pages3
JournalJournal of Clinical Microbiology
Volume38
Issue number2
Publication statusPublished - 16 Feb 2000
Externally publishedYes

Cite this

Connerton, P., Wain, J., Hien, T. T., Ali, T., Parry, C., Chinh, N. T., Vinh, H., Ho, V. A., Diep, T. S., Day, N. P. J., White, N. J., Dougan, G., & Farrar, J. J. (2000). Epidemic typhoid in Vietnam: Molecular typing of multiple-antibiotic- resistant Salmonella enterica serotype typhi from four outbreaks. Journal of Clinical Microbiology, 38(2), 895-897.