Enrichment of (E)-resveratrol from peanut byproduct with molecularly imprinted polymers

Lachlan Schwarz; Basil Danylec; Yuanzhong Yang; Simon Harris; Reinhard Boysen; Milton Thomas William Hearn

doi:10.1021/jf104230f

Enrichment of (E)-resveratrol from peanut byproduct with molecularly imprinted polymers

Lachlan Schwarz, Basil Danylec, Yuanzhong Yang, Simon Harris, Reinhard Boysen, Milton Thomas William Hearn

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

Molecularly imprinted solid phase extraction (MISPE) has been employed to isolate and concentrate bioactive polyphenols from peanut press waste. To this end, a molecularly imprinted polymer (MIP) templated with the phytoalexin (E)-resveratrol has been prepared via self-assembly with the functional monomer 4-vinylpyridine (4VP) in a 1:3 molar ratio. Subsequent molecular interrogation of the MIP binding sites demonstrated preferential structural selectivity for (E)-resveratrol with respect to other structurally related naturally occurring compounds. This selectivity was subsequently exploited to achieve substantial sample cleanup of peanut press waste under aqueous conditions with significant enrichment of (E)-resveratrol (>60 fold) requiring minimal sample preparation.

Original language	English
Pages (from-to)	3539 - 3543
Number of pages	5
Journal	Journal of Agricultural and Food Chemistry
Volume	59
Issue number	8
DOIs	https://doi.org/10.1021/jf104230f
Publication status	Published - 2011

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abstract = "Molecularly imprinted solid phase extraction (MISPE) has been employed to isolate and concentrate bioactive polyphenols from peanut press waste. To this end, a molecularly imprinted polymer (MIP) templated with the phytoalexin (E)-resveratrol has been prepared via self-assembly with the functional monomer 4-vinylpyridine (4VP) in a 1:3 molar ratio. Subsequent molecular interrogation of the MIP binding sites demonstrated preferential structural selectivity for (E)-resveratrol with respect to other structurally related naturally occurring compounds. This selectivity was subsequently exploited to achieve substantial sample cleanup of peanut press waste under aqueous conditions with significant enrichment of (E)-resveratrol (>60 fold) requiring minimal sample preparation.",

author = "Lachlan Schwarz and Basil Danylec and Yuanzhong Yang and Simon Harris and Reinhard Boysen and Hearn, {Milton Thomas William}",

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T1 - Enrichment of (E)-resveratrol from peanut byproduct with molecularly imprinted polymers

AU - Schwarz, Lachlan

AU - Danylec, Basil

AU - Yang, Yuanzhong

AU - Harris, Simon

AU - Boysen, Reinhard

AU - Hearn, Milton Thomas William

PY - 2011

Y1 - 2011

N2 - Molecularly imprinted solid phase extraction (MISPE) has been employed to isolate and concentrate bioactive polyphenols from peanut press waste. To this end, a molecularly imprinted polymer (MIP) templated with the phytoalexin (E)-resveratrol has been prepared via self-assembly with the functional monomer 4-vinylpyridine (4VP) in a 1:3 molar ratio. Subsequent molecular interrogation of the MIP binding sites demonstrated preferential structural selectivity for (E)-resveratrol with respect to other structurally related naturally occurring compounds. This selectivity was subsequently exploited to achieve substantial sample cleanup of peanut press waste under aqueous conditions with significant enrichment of (E)-resveratrol (>60 fold) requiring minimal sample preparation.

AB - Molecularly imprinted solid phase extraction (MISPE) has been employed to isolate and concentrate bioactive polyphenols from peanut press waste. To this end, a molecularly imprinted polymer (MIP) templated with the phytoalexin (E)-resveratrol has been prepared via self-assembly with the functional monomer 4-vinylpyridine (4VP) in a 1:3 molar ratio. Subsequent molecular interrogation of the MIP binding sites demonstrated preferential structural selectivity for (E)-resveratrol with respect to other structurally related naturally occurring compounds. This selectivity was subsequently exploited to achieve substantial sample cleanup of peanut press waste under aqueous conditions with significant enrichment of (E)-resveratrol (>60 fold) requiring minimal sample preparation.

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VL - 59

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EP - 3543

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

IS - 8

ER -

Enrichment of (E)-resveratrol from peanut byproduct with molecularly imprinted polymers

Abstract

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