Enhanced stabilization of the Tobacco mosaic virus using protic ionic liquids

Nolene Byrne, Brendan Rodoni, Fiona Constable, Swapna Varghese, James H Davis

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)


We report on the use of protic ionic liquids, pILs, as solvents for the solubilisation and stabilization of viruses. We show that the shelf life of the pIL stabilized tobacco mosaic virus is significantly enhanced when compared to traditional phosphate buffer. This has new opportunities for the preparation, characterization and storage of viruses and virus based technologies.

Original languageEnglish
Pages (from-to)10119-10121
Number of pages3
JournalPhysical Chemistry Chemical Physics
Issue number29
Publication statusPublished - 7 Aug 2012
Externally publishedYes

Cite this