Enhanced nanoparticle-oligonucleotide conjugates for DNA nanomachine controlled surface-enhanced Raman scattering switch

Zhiliang Zhang; Yongqiang Wen; Ying Ma; Jia Luo; Xingye Zhang; Lei Jiang; Yanlin Song

doi:10.1063/1.3573827

Enhanced nanoparticle-oligonucleotide conjugates for DNA nanomachine controlled surface-enhanced Raman scattering switch

Zhiliang Zhang
, Yongqiang Wen
, Ying Ma
, Jia Luo
, Xingye Zhang
, Lei Jiang
, Yanlin Song

Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)

Abstract

In this letter, a pH -responsive surface-enhanced Raman scattering (SERS) switching system based on the controlled organization of silver nanoparticles (AgNPs) by DNA nanomachine has been designed. In this system, the polyvalent linkages between AgNPs and cyclic disulfide groups-modified DNA tremendously increased the stability of the AgNP-DNA conjugates. Using this kind of conjugates, the SERS enhancement was demonstrated with good controllability and reproducibility through the controlled formation/deformation of SERS "hotspots" by the adjustment of pH of aqueous media.

Original language	English
Article number	133704
Journal	Applied Physics Letters
Volume	98
Issue number	13
DOIs	https://doi.org/10.1063/1.3573827
Publication status	Published - 28 Mar 2011
Externally published	Yes

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10.1063/1.3573827

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abstract = "In this letter, a pH -responsive surface-enhanced Raman scattering (SERS) switching system based on the controlled organization of silver nanoparticles (AgNPs) by DNA nanomachine has been designed. In this system, the polyvalent linkages between AgNPs and cyclic disulfide groups-modified DNA tremendously increased the stability of the AgNP-DNA conjugates. Using this kind of conjugates, the SERS enhancement was demonstrated with good controllability and reproducibility through the controlled formation/deformation of SERS {"}hotspots{"} by the adjustment of pH of aqueous media.",

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T1 - Enhanced nanoparticle-oligonucleotide conjugates for DNA nanomachine controlled surface-enhanced Raman scattering switch

AU - Zhang, Zhiliang

AU - Wen, Yongqiang

AU - Ma, Ying

AU - Luo, Jia

AU - Zhang, Xingye

AU - Jiang, Lei

AU - Song, Yanlin

PY - 2011/3/28

Y1 - 2011/3/28

N2 - In this letter, a pH -responsive surface-enhanced Raman scattering (SERS) switching system based on the controlled organization of silver nanoparticles (AgNPs) by DNA nanomachine has been designed. In this system, the polyvalent linkages between AgNPs and cyclic disulfide groups-modified DNA tremendously increased the stability of the AgNP-DNA conjugates. Using this kind of conjugates, the SERS enhancement was demonstrated with good controllability and reproducibility through the controlled formation/deformation of SERS "hotspots" by the adjustment of pH of aqueous media.

AB - In this letter, a pH -responsive surface-enhanced Raman scattering (SERS) switching system based on the controlled organization of silver nanoparticles (AgNPs) by DNA nanomachine has been designed. In this system, the polyvalent linkages between AgNPs and cyclic disulfide groups-modified DNA tremendously increased the stability of the AgNP-DNA conjugates. Using this kind of conjugates, the SERS enhancement was demonstrated with good controllability and reproducibility through the controlled formation/deformation of SERS "hotspots" by the adjustment of pH of aqueous media.

UR - https://www.scopus.com/pages/publications/79953735472

U2 - 10.1063/1.3573827

DO - 10.1063/1.3573827

M3 - Article

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VL - 98

JO - Applied Physics Letters

JF - Applied Physics Letters

IS - 13

M1 - 133704

ER -

Enhanced nanoparticle-oligonucleotide conjugates for DNA nanomachine controlled surface-enhanced Raman scattering switch

Abstract

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