Engraving our first B cell memories into the repertoire

Kim L. Good-Jacobson

doi:10.1016/j.it.2021.09.009

Engraving our first B cell memories into the repertoire

Kim L. Good-Jacobson

Research output: Contribution to journal › Short Survey › Other › peer-review

1 Citation (Scopus)

Abstract

Memory B cells are central to effective protection against reinfection. Glaros et al. used single-cell techniques to illuminate how activated mouse B cells are diverted into forming memory cells a few days post-immunogenic exposure. Early memory subsets contribute to a crucial goal: building a diverse and agile humoral defense system.

Original language	English
Pages (from-to)	951-952
Number of pages	2
Journal	Trends in Immunology
Volume	42
Issue number	11
DOIs	https://doi.org/10.1016/j.it.2021.09.009
Publication status	Published - Nov 2021

Keywords

activated B cells
germinal center-independent
memory B cell
plasmablasts
single-cell RNA sequencing

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10.1016/j.it.2021.09.009

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title = "Engraving our first B cell memories into the repertoire",

abstract = "Memory B cells are central to effective protection against reinfection. Glaros et al. used single-cell techniques to illuminate how activated mouse B cells are diverted into forming memory cells a few days post-immunogenic exposure. Early memory subsets contribute to a crucial goal: building a diverse and agile humoral defense system.",

keywords = "activated B cells, germinal center-independent, memory B cell, plasmablasts, single-cell RNA sequencing",

author = "Good-Jacobson, {Kim L.}",

note = "Funding Information: K.L.G-J is supported by a Bellberry-Viertel Senior Medical Research Fellowship . Illustration created with BioRender.com . Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

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language = "English",

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AU - Good-Jacobson, Kim L.

N1 - Funding Information: K.L.G-J is supported by a Bellberry-Viertel Senior Medical Research Fellowship . Illustration created with BioRender.com . Publisher Copyright: © 2021 Elsevier Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/11

Y1 - 2021/11

N2 - Memory B cells are central to effective protection against reinfection. Glaros et al. used single-cell techniques to illuminate how activated mouse B cells are diverted into forming memory cells a few days post-immunogenic exposure. Early memory subsets contribute to a crucial goal: building a diverse and agile humoral defense system.

AB - Memory B cells are central to effective protection against reinfection. Glaros et al. used single-cell techniques to illuminate how activated mouse B cells are diverted into forming memory cells a few days post-immunogenic exposure. Early memory subsets contribute to a crucial goal: building a diverse and agile humoral defense system.

KW - activated B cells

KW - germinal center-independent

KW - memory B cell

KW - plasmablasts

KW - single-cell RNA sequencing

UR - http://www.scopus.com/inward/record.url?scp=85116679786&partnerID=8YFLogxK

U2 - 10.1016/j.it.2021.09.009

DO - 10.1016/j.it.2021.09.009

M3 - Short Survey

AN - SCOPUS:85116679786

SN - 1471-4906

VL - 42

SP - 951

EP - 952

JO - Trends in Immunology

JF - Trends in Immunology

IS - 11

ER -

Engraving our first B cell memories into the repertoire

Abstract

Keywords

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