Engineering and measuring systemic multi-organ interactions for translational applications

Lor Huai Chong, Hsih Yin Tan, Louis Ong, Christopher Tostado, Yi Chin Toh

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

Abstract

Human physiology and pathophysiology often involve systemic interactions between multiple organs or tissues, such as microbial-host interactions and metabolic crosstalk. While microfluidic platforms attractive to recapitulate these biological crosstalk, functional specifications and assay readouts must also be considered for the eventual translation of these devices. In this talk, a design thinking approach to the development of microfluidic multi-organ systems will be presented in the context of several drug testing or disease modeling scenario.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages11-12
Number of pages2
ISBN (Electronic)9781733419017
Publication statusPublished - 2020
Externally publishedYes
EventInternational Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020) - Virtual, United States of America
Duration: 4 Oct 20209 Oct 2020
Conference number: 24th
https://microtas2020.org (Website)
https://pubs.acs.org/toc/aamick/10/48?ref=breadcrumb (Proceedings)

Conference

ConferenceInternational Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020)
Abbreviated titleMicroTAS 2020
Country/TerritoryUnited States of America
Period4/10/209/10/20
Internet address

Keywords

  • Disease modeling
  • Drug screening
  • Microfluidics
  • Modular
  • Multi-organ interactions

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