@article{dab4534eba724eaab87472d5a5a23f0f,
title = "Engine-trailer-structured nanotrucks for efficient nano-bio interactions and bioimaging-guided drug delivery",
abstract = "We have rationally fabricated an asymmetric structured mesoporous nanotruck by the interfacial-energy-mediated anisotropic growth strategy. This nanotruck possesses distinguished dual domains: (1) spherical SiO2 head with a rough surface as an engine for enhanced nano-bio interactions and (2) a periodic mesoporous organosilica nanorod with high surface area as a trailer for efficient drug loading. The nanotrucks can be further functionalized by embedding functional nanoparticles in the rough heads and exhibit great potentials in biomedicine.",
keywords = "asymmetric nanomaterials, drug delivery, mesoporous silica, rough surfaces, SDG3: Good health and well-being",
author = "Wenxing Wang and Peiyuan Wang and Liang Chen and Mengyao Zhao and Hung, \{Chin Te\} and Chengzhong Yu and Al-Khalaf, \{Areej Abdulkareem\} and Hozzein, \{Wael N.\} and Fan Zhang and Xiaomin Li and Dongyuan Zhao",
note = "Funding Information: The work was supported by NSFC , China (grant no. 21875043 , 21701027 , 21733003 , 21905052 , 51961145403 ), China National Key Basic Research Program (973 Project), China (no. 2018YFA0209401 , 2017YFA0207303 ), Key Basic Research Program of Science and Technology Commission of Shanghai Municipality , China ( 17JC1400100 ), Science and Technology Commission of Shanghai Municipality , China ( 18ZR1404600 , 16520710100 ), and China Postdoctoral Science Foundation , China ( 2018M630397 ). This work was funded by the Deanship of Scientific Research at Princess Nourah Bint Abdulrahman University , Saudi Arabia, through the Research Groups Program grant no. RGP-1438-0006 . Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = may,
day = "14",
doi = "10.1016/j.chempr.2020.01.010",
language = "English",
volume = "6",
pages = "1097--1112",
journal = "Chem",
issn = "2451-9308",
publisher = "Cell Press",
number = "5",
}