Endophytes from Malaysian medicinal plants as sources for discovery of anticancer agents

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Abstract

Malaysia hosts a diverse range of medicinal plants having therapeutic values including anticancer properties. Over the years, a group of microorganisms called endophytes producing bioactive compounds similar to their host plants has been discovered. These endophytes, producing important compounds such as Taxol, L-asparaginase, and sclerotiorin, can be isolated and cultured in largescale to produce valuable compounds. This alternative approach of producing bioactive compounds is more sustainable than plants, as endophytes are renewable sources. In this chapter, endophytes from Malaysian medicinal plants have been discussed, highlighting the diversity of endophytes, the valuable compounds produced, the current methods used in biosourcing of endophytes, and the future prospects of anticancer agents derived from endophytes of Malaysian medicinal plants.
Original languageEnglish
Title of host publicationMedicinal Plants and Fungi
Subtitle of host publicationRecent Advances in Research and Development
EditorsDinesh Chandra Agrawal, Hsin-Sheng Tsay, Lie-Fen Shyur, Yang-Chang Wu, Sheng-Yang Wang
Place of PublicationSingapore
PublisherSpringer
Chapter10
Pages313-335
Number of pages23
ISBN (Electronic)9789811059780
ISBN (Print)9789811059773
DOIs
Publication statusPublished - 2017

Publication series

NameMedicinal and Aromatic Plants of the World
PublisherSpringer Nature Singapore
Volume4
ISSN (Print)2352-6831
ISSN (Electronic)2352-684X

Keywords

  • endophytes
  • medicinal plants
  • Anticancer agent

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