Endolichenic fungi from common lichens as new sources for valuable bio-active compounds

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Abstract

Lichens are known to produce bio-active compounds. However, their natural slow growth limited progress in researching lead compounds from lichens for drug development. In recent years, a rare group of fungi were found to grow in the lichens, identified as endolichenic fungi (EF). The discovery of this group of fungi is relatively new but has attracted notable attention attributed to their phar macological potential (antimicrobial, antiviral, antioxidant, and antitumor). Interestingly, these endolichenic fungi produce bio-active compounds that may be distinct from those produced by their host lichens. With an estimate of 20,000 known lichens reported worldwide, there are tremendous opportunities to discover valuable endolichenic fungi. Thus, the aim of present chapter is to provide an overview on the progress and advances made in the research of endolichenic fungi. Also, it discusses on the emerging biotechnological approaches to explore endolichenic fungi.

Original languageEnglish
Title of host publicationNatural Bio-active Compounds
Subtitle of host publicationVolume 1: Production and Applications
EditorsMohd Sayeed Akhtar, Mallappa Kumara Swamy, Uma Rani Sinniah
Place of PublicationSingapore
PublisherSpringer-Verlag London Ltd.
Chapter4
Pages105-127
Number of pages23
Volume1
Edition1st
ISBN (Electronic)9789811371547
ISBN (Print)9789811371530
DOIs
Publication statusPublished - 7 Sep 2019

Keywords

  • Bio-active compounds
  • Biodiversity
  • Biotechnology
  • Conservation
  • Lichens

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