Endocrine and metabolic response to surgery and its management

Maurizio Pacilli, Ian E. Willetts

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

3 Citations (Scopus)


The physiological and biochemical events which occur in the child undergoing surgical interventions are multifaceted, inter-relational and complex. Many serve to facilitate the recovery and survival of the child undergoing a surgical stress. However, when unchecked, some can result in patient morbidity and increased mortality. The advent of minimally-invasive surgical practice has further added to the interest that such techniques may blunt the potential adverse response in the child to traditional surgical stresses. Much scientific endeavor has been spent in investigating these, as yet not fully understood, responses in the human child. This chapter explores the knowledge available concerning the child's responses to the trauma of surgery and attempts to provide practical insight into the management of these physiological challenges for the clinician.

Original languageEnglish
Title of host publicationPediatric Urology: Surgical Complications and Management: Second Edition
EditorsPrasad P. Godbole, Martin A. Koyle, Duncan T. Wilcox
Number of pages13
ISBN (Electronic)9781118473382
ISBN (Print)9781118473313
Publication statusPublished - 24 Apr 2015
Externally publishedYes


  • Anabolism
  • Carbohydrates
  • Catabolism
  • Electrolyte balance
  • Fluid management
  • Lipids and proteins mobilization
  • Salt and water retention
  • Stress response
  • Surgical trauma

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