Enantioselective total synthesis of the mexicanolides: Khayasin, proceranolide, and mexicanolide

Jonathan M. Faber; Wilhelm A. Eger; Craig M. Williams

doi:10.1021/jo301182f

Enantioselective total synthesis of the mexicanolides: Khayasin, proceranolide, and mexicanolide

Jonathan M. Faber, Wilhelm A. Eger, Craig M. Williams

Research output: Contribution to journal › Article › Research › peer-review

42 Citations (Scopus)

Abstract

The enantioselective total synthesis of the limonoids khayasin, proceranolide and mexicanolide was achieved via a convergent strategy utilizing a tactic aimed at incorporating natural products as advanced intermediates. This extended biomimetically inspired approach additionally achieved the enantioselective total synthesis of the intermediates azedaralide and cipadonoid B.

Original language	English
Pages (from-to)	8913-8921
Number of pages	9
Journal	The Journal of Organic Chemistry
Volume	77
Issue number	20
DOIs	https://doi.org/10.1021/jo301182f
Publication status	Published - 19 Oct 2012
Externally published	Yes

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title = "Enantioselective total synthesis of the mexicanolides: Khayasin, proceranolide, and mexicanolide",

abstract = "The enantioselective total synthesis of the limonoids khayasin, proceranolide and mexicanolide was achieved via a convergent strategy utilizing a tactic aimed at incorporating natural products as advanced intermediates. This extended biomimetically inspired approach additionally achieved the enantioselective total synthesis of the intermediates azedaralide and cipadonoid B.",

author = "Faber, {Jonathan M.} and Eger, {Wilhelm A.} and Williams, {Craig M.}",

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AU - Eger, Wilhelm A.

AU - Williams, Craig M.

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AB - The enantioselective total synthesis of the limonoids khayasin, proceranolide and mexicanolide was achieved via a convergent strategy utilizing a tactic aimed at incorporating natural products as advanced intermediates. This extended biomimetically inspired approach additionally achieved the enantioselective total synthesis of the intermediates azedaralide and cipadonoid B.

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Enantioselective total synthesis of the mexicanolides: Khayasin, proceranolide, and mexicanolide

Abstract

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