Enantioselective synthesis of a potential key intermediate for the total synthesis of fumagillin

Marisa Daniela Ciampini, Patrick Perlmutter, Keith G Watson

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)


Key intermediate, 7, of a projected total synthesis of the anti-angiogenesis compound Fumagillin 1 and the semi-synthetic analogue TNP-470 2, has been prepared in enantiornerically pure form by employing an early nucleophilic addition ring closure [NARC] sequence to construct the cyclohexene backbone. Crown Copyright (c) 2007 Published by Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)243 - 250
Number of pages8
Issue number2
Publication statusPublished - 2007

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