Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease

Izelle Labuschagne; Rebecca Jones; Jennifer Callaghan; Daisy Whitehead; Eve M Dumas; Miranda J Say; Ellen P Hart; Damian Justo; Allison Coleman; Rachelle C Dar Santos; Chris Frost; David O Craufurd; Sarah J Tabrizi; Julie C Stout

doi:10.1016/j.psychres.2012.09.022

Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease

Izelle Labuschagne, Rebecca Jones, Jennifer Callaghan, Daisy Whitehead, Eve M Dumas, Miranda J Say, Ellen P Hart, Damian Justo, Allison Coleman, Rachelle C Dar Santos, Chris Frost, David O Craufurd, Sarah J Tabrizi, Julie C Stout

School of Psychological Sciences

Research output: Contribution to journal › Article › Research › peer-review

47 Citations (Scopus)

Abstract

Facial emotion recognition impairments have been reported in Huntington s disease (HD). However, the nature of the impairments across the spectrum of HD remains unclear. We report on emotion recognition data from 344 participants comprising premanifest HD (PreHD) and early HD patients, and controls. In a test of recognition of facial emotions, we examined responses to six basic emotional expressions and neutral expressions. In addition, and within the early HD sample, we tested for differences on emotion recognition performance between those `on? vs. `off? neuroleptic or selective serotonin reuptake inhibitor (SSRI) medications. The PreHD groups showed significant (p

Original language	English
Pages (from-to)	118 - 126
Number of pages	9
Journal	Psychiatry Research
Volume	207
Issue number	1-2
DOIs	https://doi.org/10.1016/j.psychres.2012.09.022
Publication status	Published - 2013

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Labuschagne, I., Jones, R., Callaghan, J., Whitehead, D., Dumas, E. M., Say, M. J., Hart, E. P., Justo, D., Coleman, A., Dar Santos, R. C., Frost, C., Craufurd, D. O., Tabrizi, S. J., & Stout, J. C. (2013). Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease. Psychiatry Research, 207(1-2), 118 - 126. https://doi.org/10.1016/j.psychres.2012.09.022

@article{022782670a794fe8b904d55e146a0186,

title = "Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease",

abstract = "Facial emotion recognition impairments have been reported in Huntington s disease (HD). However, the nature of the impairments across the spectrum of HD remains unclear. We report on emotion recognition data from 344 participants comprising premanifest HD (PreHD) and early HD patients, and controls. In a test of recognition of facial emotions, we examined responses to six basic emotional expressions and neutral expressions. In addition, and within the early HD sample, we tested for differences on emotion recognition performance between those `on? vs. `off? neuroleptic or selective serotonin reuptake inhibitor (SSRI) medications. The PreHD groups showed significant (p",

author = "Izelle Labuschagne and Rebecca Jones and Jennifer Callaghan and Daisy Whitehead and Dumas, {Eve M} and Say, {Miranda J} and Hart, {Ellen P} and Damian Justo and Allison Coleman and {Dar Santos}, {Rachelle C} and Chris Frost and Craufurd, {David O} and Tabrizi, {Sarah J} and Stout, {Julie C}",

year = "2013",

doi = "10.1016/j.psychres.2012.09.022",

language = "English",

volume = "207",

pages = "118 -- 126",

journal = "Psychiatry Research",

issn = "0165-1781",

publisher = "Elsevier",

number = "1-2",

}

Labuschagne, I, Jones, R, Callaghan, J, Whitehead, D, Dumas, EM, Say, MJ, Hart, EP, Justo, D, Coleman, A, Dar Santos, RC, Frost, C, Craufurd, DO, Tabrizi, SJ & Stout, JC 2013, 'Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease', Psychiatry Research, vol. 207, no. 1-2, pp. 118 - 126. https://doi.org/10.1016/j.psychres.2012.09.022

TY - JOUR

T1 - Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease

AU - Labuschagne, Izelle

AU - Jones, Rebecca

AU - Callaghan, Jennifer

AU - Whitehead, Daisy

AU - Dumas, Eve M

AU - Say, Miranda J

AU - Hart, Ellen P

AU - Justo, Damian

AU - Coleman, Allison

AU - Dar Santos, Rachelle C

AU - Frost, Chris

AU - Craufurd, David O

AU - Tabrizi, Sarah J

AU - Stout, Julie C

PY - 2013

Y1 - 2013

N2 - Facial emotion recognition impairments have been reported in Huntington s disease (HD). However, the nature of the impairments across the spectrum of HD remains unclear. We report on emotion recognition data from 344 participants comprising premanifest HD (PreHD) and early HD patients, and controls. In a test of recognition of facial emotions, we examined responses to six basic emotional expressions and neutral expressions. In addition, and within the early HD sample, we tested for differences on emotion recognition performance between those `on? vs. `off? neuroleptic or selective serotonin reuptake inhibitor (SSRI) medications. The PreHD groups showed significant (p

AB - Facial emotion recognition impairments have been reported in Huntington s disease (HD). However, the nature of the impairments across the spectrum of HD remains unclear. We report on emotion recognition data from 344 participants comprising premanifest HD (PreHD) and early HD patients, and controls. In a test of recognition of facial emotions, we examined responses to six basic emotional expressions and neutral expressions. In addition, and within the early HD sample, we tested for differences on emotion recognition performance between those `on? vs. `off? neuroleptic or selective serotonin reuptake inhibitor (SSRI) medications. The PreHD groups showed significant (p

UR - http://www.sciencedirect.com/science/article/pii/S0165178112005197

U2 - 10.1016/j.psychres.2012.09.022

DO - 10.1016/j.psychres.2012.09.022

M3 - Article

SN - 0165-1781

VL - 207

SP - 118

EP - 126

JO - Psychiatry Research

JF - Psychiatry Research

IS - 1-2

ER -

Emotional face recognition deficits and medication effects in pre-manifest through stage-II Huntington's disease

Abstract

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