Abstract
The biosynthetic pathway to 4-methoxy-2,2′-bipyrrole-5-carboxaldehyde (MBC), a key intermediate in the biosynthesis of prodiginine antibiotics in Streptomyces coelicolor, has been elucidated using a combination of gene replacements and feeding experiments with chemically synthesised MBC and a synthetic analogue of a pathway intermediate.
Original language | English |
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Pages (from-to) | 3981-3983 |
Number of pages | 3 |
Journal | Chemical Communications |
Issue number | 38 |
DOIs | |
Publication status | Published - 3 Oct 2006 |
Externally published | Yes |