Electroretinograms of albino and pigmented guinea-pigs (Cavia porcellus)

Bang V. Bui, Andrew J. Sinclair, Algis J. Vingrys

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)


Purpose/Methods: The present study compares the electroretinogram responses of albino and pigmented guinea-pigs (Carla porcellus) with data published for the rat and mouse. Result: We found that albino guinea-pigs gave significantly larger amplitudes and faster implicit times for a-wave and peak-to-peak responses than did pigmented animals. In contrast, pigmented and albino rats and mice do not show such differences between strains. Conclusion: We suggest that the guinea-pig may be a better model of the retinal response in human albinism as their response characteristics are consistent with those published for humans.

Original languageEnglish
Pages (from-to)S98-S100
Number of pages3
JournalAustralian and New Zealand Journal of Ophthalmology
Issue numberSUPPL. 1
Publication statusPublished - 1 Jan 1998
Externally publishedYes


  • Albino
  • Electroretinography
  • Guinea-pig
  • Intensity response function

Cite this