Electroretinograms of albino and pigmented guinea-pigs (Cavia porcellus)

Bang V. Bui; Andrew J. Sinclair; Algis J. Vingrys

doi:10.1111/j.1442-9071.1998.tb01388.x

Electroretinograms of albino and pigmented guinea-pigs (Cavia porcellus)

Bang V. Bui, Andrew J. Sinclair, Algis J. Vingrys

Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)

Abstract

Purpose/Methods: The present study compares the electroretinogram responses of albino and pigmented guinea-pigs (Carla porcellus) with data published for the rat and mouse. Result: We found that albino guinea-pigs gave significantly larger amplitudes and faster implicit times for a-wave and peak-to-peak responses than did pigmented animals. In contrast, pigmented and albino rats and mice do not show such differences between strains. Conclusion: We suggest that the guinea-pig may be a better model of the retinal response in human albinism as their response characteristics are consistent with those published for humans.

Original language	English
Pages (from-to)	S98-S100
Number of pages	3
Journal	Australian and New Zealand Journal of Ophthalmology
Volume	26
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1111/j.1442-9071.1998.tb01388.x
Publication status	Published - 1 Jan 1998
Externally published	Yes

Keywords

Albino
Electroretinography
Guinea-pig
Intensity response function

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10.1111/j.1442-9071.1998.tb01388.x

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abstract = "Purpose/Methods: The present study compares the electroretinogram responses of albino and pigmented guinea-pigs (Carla porcellus) with data published for the rat and mouse. Result: We found that albino guinea-pigs gave significantly larger amplitudes and faster implicit times for a-wave and peak-to-peak responses than did pigmented animals. In contrast, pigmented and albino rats and mice do not show such differences between strains. Conclusion: We suggest that the guinea-pig may be a better model of the retinal response in human albinism as their response characteristics are consistent with those published for humans.",

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AU - Sinclair, Andrew J.

AU - Vingrys, Algis J.

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Y1 - 1998/1/1

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AB - Purpose/Methods: The present study compares the electroretinogram responses of albino and pigmented guinea-pigs (Carla porcellus) with data published for the rat and mouse. Result: We found that albino guinea-pigs gave significantly larger amplitudes and faster implicit times for a-wave and peak-to-peak responses than did pigmented animals. In contrast, pigmented and albino rats and mice do not show such differences between strains. Conclusion: We suggest that the guinea-pig may be a better model of the retinal response in human albinism as their response characteristics are consistent with those published for humans.

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KW - Electroretinography

KW - Guinea-pig

KW - Intensity response function

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ER -

Electroretinograms of albino and pigmented guinea-pigs (Cavia porcellus)

Abstract

Keywords

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