Abstract
Purpose/Methods: The present study compares the electroretinogram responses of albino and pigmented guinea-pigs (Carla porcellus) with data published for the rat and mouse. Result: We found that albino guinea-pigs gave significantly larger amplitudes and faster implicit times for a-wave and peak-to-peak responses than did pigmented animals. In contrast, pigmented and albino rats and mice do not show such differences between strains. Conclusion: We suggest that the guinea-pig may be a better model of the retinal response in human albinism as their response characteristics are consistent with those published for humans.
| Original language | English |
|---|---|
| Pages (from-to) | S98-S100 |
| Number of pages | 3 |
| Journal | Australian and New Zealand Journal of Ophthalmology |
| Volume | 26 |
| Issue number | SUPPL. 1 |
| DOIs | |
| Publication status | Published - 1 Jan 1998 |
| Externally published | Yes |
Keywords
- Albino
- Electroretinography
- Guinea-pig
- Intensity response function