Abstract
In a prospective study of solid-organ transplant recipients (n 22; 15 hepatic and 7 renal) receiving valganciclovir for cytomegalovirus
(CMV) prophylaxis, electronic estimation of glomerular filtration rate (eGFR) underestimated the true GFR (24-h urine
creatinine clearance) by>20 in 14/22 (63.6 ). Its use was associated with inappropriate underdosing of valganciclovir, while
the Cockroft-Gault equation was accurate in 21/22 patients (95.4 ). Subtherapeutic ganciclovir levels (
Original language | English |
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Pages (from-to) | 4058 - 4060 |
Number of pages | 3 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 57 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2013 |