Electric field-induced translocation of single-stranded DNA through a polarized carbon nanotube membrane

Yinghong Xie, Yong Kong, A. K. Soh, Huajian Gao

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31 Citations (Scopus)

Abstract

Molecular dynamics simulations based on a novel polarizable nanotube model were performed to study the dynamics in translocation of a single-stranded deoxyribonucleic acid oligonucleotide through a polarized carbon nanotube membrane by an applied electric field. The study revealed a nonlinear dependence of translocation velocity and an inverse quadratic dependence of translocation time on the electric field strength, as well as a threshold electric field below which the translocation process becomes impossible. The translocation rate was found to be pore-size dependent. The polarizable nanotube model developed for this study provides a useful platform for investigating the dynamics of a range of bionanosystems.

Original languageEnglish
Article number225101
JournalJournal of Chemical Physics
Volume127
Issue number22
DOIs
Publication statusPublished - 2007
Externally publishedYes

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