Abstract
Molecular dynamics simulations based on a novel polarizable nanotube model were performed to study the dynamics in translocation of a single-stranded deoxyribonucleic acid oligonucleotide through a polarized carbon nanotube membrane by an applied electric field. The study revealed a nonlinear dependence of translocation velocity and an inverse quadratic dependence of translocation time on the electric field strength, as well as a threshold electric field below which the translocation process becomes impossible. The translocation rate was found to be pore-size dependent. The polarizable nanotube model developed for this study provides a useful platform for investigating the dynamics of a range of bionanosystems.
Original language | English |
---|---|
Article number | 225101 |
Journal | The Journal of Chemical Physics |
Volume | 127 |
Issue number | 22 |
DOIs | |
Publication status | Published - 2007 |
Externally published | Yes |