Efficient Rh(II) binaphthol phosphate catalysts for enantioselective intramolecular tandem carbonyl ylide formation-cycloaddition of α-diazo-β-keto esters

David M. Hodgson, Paul A. Stupple, Craig Johnstone

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Catalytic enantioselective tandem carbonyl ylide formation-cycloadditions of α-diazo-β-keto ester 1 using 0.5 mol% dirhodium tetrakis(1,1'-binaphthyl-2,2'-diyl phosphate) catalysts 7-9 and 14 to give the cycloadduct 3 in good yields and up to 90% ee are described.

Original languageEnglish
Pages (from-to)2185-2186
Number of pages2
JournalChemical Communications
Issue number21
Publication statusPublished - 7 Nov 1999
Externally publishedYes

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