Efficient cell reprogramming using bioengineered surfaces

David Horna; Juan Carlos Ramirez; Anna Cifuentes Rius; Antonio Bernad; Salvador Borros; Manuel A. Gonzalez

doi:10.1002/adhm.201200017

Efficient cell reprogramming using bioengineered surfaces

David Horna, Juan Carlos Ramirez, Anna Cifuentes Rius, Antonio Bernad, Salvador Borros, Manuel A. Gonzalez

Research output: Contribution to journal › Article › Research › peer-review

11 Citations (Scopus)

Abstract

A novel method for cell reprogramming is been developed by immobilizing nucleic acid transfer vectors containing free amino groups, like lentiviral particles, onto pentafluorophenyl methacrylate (PFM)-modified surfaces obtained by PFM grafting affter Ar plasma treatment. This technique is able to reprogram murine somatic cells into pluripotent cells at high efficiencies. We call these modified surfaces cell reprogramming surfaces, or CRS.

Original language	English
Pages (from-to)	177-182
Number of pages	6
Journal	Advanced Healthcare Materials
Volume	1
Issue number	2
DOIs	https://doi.org/10.1002/adhm.201200017
Publication status	Published - 1 Mar 2012
Externally published	Yes

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title = "Efficient cell reprogramming using bioengineered surfaces",

abstract = "A novel method for cell reprogramming is been developed by immobilizing nucleic acid transfer vectors containing free amino groups, like lentiviral particles, onto pentafluorophenyl methacrylate (PFM)-modified surfaces obtained by PFM grafting affter Ar plasma treatment. This technique is able to reprogram murine somatic cells into pluripotent cells at high efficiencies. We call these modified surfaces cell reprogramming surfaces, or CRS.",

author = "David Horna and Ramirez, \{Juan Carlos\} and \{Cifuentes Rius\}, Anna and Antonio Bernad and Salvador Borros and Gonzalez, \{Manuel A.\}",

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AU - Horna, David

AU - Ramirez, Juan Carlos

AU - Cifuentes Rius, Anna

AU - Bernad, Antonio

AU - Borros, Salvador

AU - Gonzalez, Manuel A.

PY - 2012/3/1

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N2 - A novel method for cell reprogramming is been developed by immobilizing nucleic acid transfer vectors containing free amino groups, like lentiviral particles, onto pentafluorophenyl methacrylate (PFM)-modified surfaces obtained by PFM grafting affter Ar plasma treatment. This technique is able to reprogram murine somatic cells into pluripotent cells at high efficiencies. We call these modified surfaces cell reprogramming surfaces, or CRS.

AB - A novel method for cell reprogramming is been developed by immobilizing nucleic acid transfer vectors containing free amino groups, like lentiviral particles, onto pentafluorophenyl methacrylate (PFM)-modified surfaces obtained by PFM grafting affter Ar plasma treatment. This technique is able to reprogram murine somatic cells into pluripotent cells at high efficiencies. We call these modified surfaces cell reprogramming surfaces, or CRS.

UR - https://www.scopus.com/pages/publications/84878658236

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DO - 10.1002/adhm.201200017

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Efficient cell reprogramming using bioengineered surfaces

Abstract

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