Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis

Y. T. Wong, S. C. Chen, Y. A. Kerdraon, P. J. Allen, M. F. McCombe, J. W. Morley, N. H. Lovell, G. J. Suaning

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

15 Citations (Scopus)

Abstract

The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 ± 29.85 nC.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages1789-1792
Number of pages4
ISBN (Print)9781424418152
Publication statusPublished - 1 Dec 2008
Externally publishedYes
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 20 Aug 200825 Aug 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Conference

Conference30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period20/08/0825/08/08

Cite this

Wong, Y. T., Chen, S. C., Kerdraon, Y. A., Allen, P. J., McCombe, M. F., Morley, J. W., ... Suaning, G. J. (2008). Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 1789-1792). [4649525] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"). IEEE, Institute of Electrical and Electronics Engineers.
Wong, Y. T. ; Chen, S. C. ; Kerdraon, Y. A. ; Allen, P. J. ; McCombe, M. F. ; Morley, J. W. ; Lovell, N. H. ; Suaning, G. J. / Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. IEEE, Institute of Electrical and Electronics Engineers, 2008. pp. 1789-1792 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").
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title = "Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis",
abstract = "The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 ± 29.85 nC.",
author = "Wong, {Y. T.} and Chen, {S. C.} and Kerdraon, {Y. A.} and Allen, {P. J.} and McCombe, {M. F.} and Morley, {J. W.} and Lovell, {N. H.} and Suaning, {G. J.}",
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Wong, YT, Chen, SC, Kerdraon, YA, Allen, PJ, McCombe, MF, Morley, JW, Lovell, NH & Suaning, GJ 2008, Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis. in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08., 4649525, Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology", IEEE, Institute of Electrical and Electronics Engineers, pp. 1789-1792, 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, Canada, 20/08/08.

Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis. / Wong, Y. T.; Chen, S. C.; Kerdraon, Y. A.; Allen, P. J.; McCombe, M. F.; Morley, J. W.; Lovell, N. H.; Suaning, G. J.

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. IEEE, Institute of Electrical and Electronics Engineers, 2008. p. 1789-1792 4649525 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

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T1 - Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis

AU - Wong, Y. T.

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N2 - The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 ± 29.85 nC.

AB - The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 ± 29.85 nC.

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Wong YT, Chen SC, Kerdraon YA, Allen PJ, McCombe MF, Morley JW et al. Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. IEEE, Institute of Electrical and Electronics Engineers. 2008. p. 1789-1792. 4649525. (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").