Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury: a systematic review and meta-analysis protocol

Amelia J. Hicks; Fiona J. Clay; Malcolm Hopwood; Mahesh Jayaram; Rachel Batty; Jennie L. Ponsford

doi:10.11124/JBISRIR-2017-003430

Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury: a systematic review and meta-analysis protocol

Amelia J. Hicks, Fiona J. Clay, Malcolm Hopwood, Mahesh Jayaram, Rachel Batty, Jennie L. Ponsford

Research output: Contribution to journal › Article › Other › peer-review

1 Citation (Scopus)

Abstract

REVIEW OBJECTIVE/QUESTION: The objective of this systematic review is to synthesize the best available evidence on the effectiveness and harms of pharmacotherapy as compared to all types of comparators for the management of neurobehavioral symptoms in post-traumatic amnesia in adults aged 16 years and over who have sustained a traumatic brain injury. This review forms part of a larger project which aims to gather the evidence for the pharmacological treatment of neurobehavioral symptoms post traumatic brain injury as a prelude to the development of a clinical guideline.

Original language	English
Pages (from-to)	2890-2912
Number of pages	23
Journal	The JBI Database of Systematic Reviews and Implementation Reports
Volume	15
Issue number	12
DOIs	https://doi.org/10.11124/JBISRIR-2017-003430
Publication status	Published - 1 Dec 2017

Access to Document

10.11124/JBISRIR-2017-003430

Link to publication in Scopus

Cite this

Hicks, A. J., Clay, F. J., Hopwood, M., Jayaram, M., Batty, R., & Ponsford, J. L. (2017). Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury: a systematic review and meta-analysis protocol. The JBI Database of Systematic Reviews and Implementation Reports, 15(12), 2890-2912. https://doi.org/10.11124/JBISRIR-2017-003430

Hicks, Amelia J. ; Clay, Fiona J. ; Hopwood, Malcolm ; Jayaram, Mahesh ; Batty, Rachel ; Ponsford, Jennie L. / Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury : a systematic review and meta-analysis protocol. In: The JBI Database of Systematic Reviews and Implementation Reports. 2017 ; Vol. 15, No. 12. pp. 2890-2912.

@article{78c955450ae147c986955706d908b4c0,

title = "Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury: a systematic review and meta-analysis protocol",

abstract = "REVIEW OBJECTIVE/QUESTION: The objective of this systematic review is to synthesize the best available evidence on the effectiveness and harms of pharmacotherapy as compared to all types of comparators for the management of neurobehavioral symptoms in post-traumatic amnesia in adults aged 16 years and over who have sustained a traumatic brain injury. This review forms part of a larger project which aims to gather the evidence for the pharmacological treatment of neurobehavioral symptoms post traumatic brain injury as a prelude to the development of a clinical guideline.",

author = "Hicks, {Amelia J.} and Clay, {Fiona J.} and Malcolm Hopwood and Mahesh Jayaram and Rachel Batty and Ponsford, {Jennie L.}",

year = "2017",

month = dec,

day = "1",

doi = "10.11124/JBISRIR-2017-003430",

language = "English",

volume = "15",

pages = "2890--2912",

journal = "JBI Evidence Synthesis",

issn = "2689-8381",

publisher = "Lippincott Williams & Wilkins",

number = "12",

}

Hicks, AJ, Clay, FJ, Hopwood, M, Jayaram, M, Batty, R & Ponsford, JL 2017, 'Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury: a systematic review and meta-analysis protocol', The JBI Database of Systematic Reviews and Implementation Reports, vol. 15, no. 12, pp. 2890-2912. https://doi.org/10.11124/JBISRIR-2017-003430

Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury : a systematic review and meta-analysis protocol. / Hicks, Amelia J.; Clay, Fiona J.; Hopwood, Malcolm; Jayaram, Mahesh; Batty, Rachel; Ponsford, Jennie L.

In: The JBI Database of Systematic Reviews and Implementation Reports, Vol. 15, No. 12, 01.12.2017, p. 2890-2912.

Research output: Contribution to journal › Article › Other › peer-review

TY - JOUR

T1 - Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury

T2 - a systematic review and meta-analysis protocol

AU - Hicks, Amelia J.

AU - Clay, Fiona J.

AU - Hopwood, Malcolm

AU - Jayaram, Mahesh

AU - Batty, Rachel

AU - Ponsford, Jennie L.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - REVIEW OBJECTIVE/QUESTION: The objective of this systematic review is to synthesize the best available evidence on the effectiveness and harms of pharmacotherapy as compared to all types of comparators for the management of neurobehavioral symptoms in post-traumatic amnesia in adults aged 16 years and over who have sustained a traumatic brain injury. This review forms part of a larger project which aims to gather the evidence for the pharmacological treatment of neurobehavioral symptoms post traumatic brain injury as a prelude to the development of a clinical guideline.

AB - REVIEW OBJECTIVE/QUESTION: The objective of this systematic review is to synthesize the best available evidence on the effectiveness and harms of pharmacotherapy as compared to all types of comparators for the management of neurobehavioral symptoms in post-traumatic amnesia in adults aged 16 years and over who have sustained a traumatic brain injury. This review forms part of a larger project which aims to gather the evidence for the pharmacological treatment of neurobehavioral symptoms post traumatic brain injury as a prelude to the development of a clinical guideline.

UR - http://www.scopus.com/inward/record.url?scp=85050426133&partnerID=8YFLogxK

U2 - 10.11124/JBISRIR-2017-003430

DO - 10.11124/JBISRIR-2017-003430

M3 - Article

C2 - 29219873

AN - SCOPUS:85050426133

VL - 15

SP - 2890

EP - 2912

JO - JBI Evidence Synthesis

JF - JBI Evidence Synthesis

SN - 2689-8381

IS - 12

ER -

Hicks AJ, Clay FJ, Hopwood M, Jayaram M, Batty R, Ponsford JL. Efficacy and harms of pharmacological interventions for neurobehavioral symptoms in post traumatic amnesia after traumatic brain injury: a systematic review and meta-analysis protocol. The JBI Database of Systematic Reviews and Implementation Reports. 2017 Dec 1;15(12):2890-2912. https://doi.org/10.11124/JBISRIR-2017-003430