Efficacy and Feasibility of a Tele-health Intervention for Acute Coronary Syndrome Patients with Depression: Results of the “MoodCare” Randomized Controlled Trial

Adrienne O'Neil, Barr Taylor, Kristy Sanderson, Sheila Cyril, Bianca Gar Yee Chan, Anna Hawkes, David L Hare, Michael V Jelinek, Kamalesh Venugopal, John J Atherton, John Amerena, Leeanne Grigg, Darren Walters, Brian Federick Oldenburg

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12 Citations (Scopus)


Purpose: We aimed to evaluate the 6-month efficacy and feasibility of a tele-health program (MoodCare) that integrates depression management into a cardiovascular disease risk reduction program for acute coronary syndrome patients with low mood.

Methods: A two-arm, parallel, randomized design was used comprising 121 patients admitted to one of six hospitals for acute coronary syndrome.

Background: Depression is common after a cardiac event, yet there remain few approaches to management that are both effective and scalable.

Results: Significant treatment effects were observed for Patient Health Questionnaire 9 (PHQ9) depression (mean difference [change] = −1.8; p = 0.025; effect size: d = 0.36) for the overall sample, when compared with usual medical care. Results were more pronounced effects for those with a history of depression (mean difference [change] = −2.7; p = 0.043; effect size: d = 0.65).

Conclusions: MoodCare was effective for improving depression in acute coronary syndrome patients, producing effect sizes exceeding those of some face-to-face psychotherapeutic interventions and pharmacotherapy. (Trial Registration Number: ACTRN1260900038623.)

Original languageEnglish
Pages (from-to)163 - 174
Number of pages12
JournalAnnals of Behavioral Medicine
Issue number2
Publication statusPublished - 2014


  • Acute coronary syndrome
  • Cardiac
  • Cognitive behavior therapy
  • Depression
  • Tele-health

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