Effects of the opioid anaesthetic alfentanil on the haemodynamic response to stimulated haemorrhage in rabbits

R. G. Evans, J. Ludbrook, A. F. Van Leeuwen

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The opioid anaesthetic alfentanil does not affect the arterial baroreflex-mediated vasoconstrictive Phase I of simulated haemorrhage, but prevents the cardiac-receptor mediated failure of vasoconstriction that occurs in Phase II. This appears to be due to an action on μ-opiate receptors in the CNS.

Original languageEnglish
Title of host publicationNew leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914
EditorsJ.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
Number of pages1
ISBN (Print)044481213X
Publication statusPublished - 1990
Externally publishedYes
EventThe International Narcotics Research Conference -
Duration: 8 Jul 198913 Jul 1989


ConferenceThe International Narcotics Research Conference

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