TY - JOUR
T1 - Effects of Quince syrup on clinical symptoms of children with symptomatic gastroesophageal reflux disease
T2 - A double-blind randomized controlled clinical trial
AU - Zohalinezhad, Mohammad Ebrahim
AU - Imanieh, Mohammad Hadi
AU - Samani, Soliman Mohammadi
AU - Mohagheghzadeh, Abdolali
AU - Dehghani, Seyed Mohsen
AU - Haghighat, Mahmoud
AU - Salehi, Alireza
AU - Faridi, Pouya
AU - Akbarzadeh, Amin Reza
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Objective: The aim of this study was to evaluate the efficacy of Quince syrup in pediatrics with symptomatic gastroesophageal reflux disease (GERD). Method: Participants (n = 80) were randomly assigned to the Quince group (0.6 cc/kg/day) or the Omeprazole group (1 cc/kg/day). Age specific questionnaires were used to assess the frequency and severity of the GERD symptoms. Mean of cumulative symptom score (CSS) at weeks 4 and 7 were compared with baseline. Results: The mean CSS value was significantly decreased from baseline in each treatment group without statistically significant differences between them. Although the mean CSS value among infants and young children was slightly decreased in the Quince group at week seven, this value was increased among children aged 5-18 years in both treatment groups without significant differences. Conclusion: Despite the effectiveness of Quince syrup in reducing symptoms in all pediatrics age groups, no significant differences were observed in comparison with the control group.
AB - Objective: The aim of this study was to evaluate the efficacy of Quince syrup in pediatrics with symptomatic gastroesophageal reflux disease (GERD). Method: Participants (n = 80) were randomly assigned to the Quince group (0.6 cc/kg/day) or the Omeprazole group (1 cc/kg/day). Age specific questionnaires were used to assess the frequency and severity of the GERD symptoms. Mean of cumulative symptom score (CSS) at weeks 4 and 7 were compared with baseline. Results: The mean CSS value was significantly decreased from baseline in each treatment group without statistically significant differences between them. Although the mean CSS value among infants and young children was slightly decreased in the Quince group at week seven, this value was increased among children aged 5-18 years in both treatment groups without significant differences. Conclusion: Despite the effectiveness of Quince syrup in reducing symptoms in all pediatrics age groups, no significant differences were observed in comparison with the control group.
KW - Children
KW - Clinical trial
KW - Cydonia oblonga Mill.
KW - Gastroesophageal reflux disease
KW - Omeprazole
KW - Traditional Persian medicine
UR - http://www.scopus.com/inward/record.url?scp=84947590224&partnerID=8YFLogxK
U2 - 10.1016/j.ctcp.2015.09.005
DO - 10.1016/j.ctcp.2015.09.005
M3 - Article
C2 - 26573454
AN - SCOPUS:84947590224
SN - 1744-3881
VL - 21
SP - 268
EP - 276
JO - Complementary Therapies in Clinical Practice
JF - Complementary Therapies in Clinical Practice
IS - 4
ER -