Effects of exercise and angiotensin-converting enzyme (ACE) on aortic stiffness in the elderly

Moran Sagiv, Nir Eynon, Michael Sagiv, Chen Yamin, Alberto Jorge Alves

Research output: Contribution to journalReview ArticleResearchpeer-review

Abstract

Senescence is a complex process involving many variables including genetics, lifestyle factors, and chronic diseases, the interaction of which significantly influences the manner in which we age (2). In particular, hypertension and genes of the rennin-angiotensin-aldosterone system have been associated with functional and structural changes of the large arteries, which are thought to contribute to age-related increases in the incidence of cardiovascular disease. Despite mounting evidence implicating sedentary behavior as a significant risk factor in chronic-disease morbidity and mortality among the elderly, there is a limited amount of information on the role of exercise in promoting optimal health and function in older people (27). The purpose of the present review is to discuss the effects of exercise training and angiotensin-converting enzyme (ACE) on aortic stiffness in the elderly.
Original languageEnglish
Pages (from-to)3-11
Number of pages9
JournalArchives of Exercise in Health and Disease
Volume1
Issue number1
Publication statusPublished - 2010
Externally publishedYes

Keywords

  • Aortic elasticity
  • angiotensin-converting enzyme
  • hypertension
  • genotype
  • exercise

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