TY - JOUR
T1 - Effects of breaking up sitting on adolescents' postprandial glucose after consuming meals varying in energy
T2 - A cross-over randomised trial
AU - Fletcher, Elly A.
AU - Salmon, Jo
AU - McNaughton, Sarah A.
AU - Orellana, Liliana
AU - Wadley, Glenn D.
AU - Bruce, Clinton
AU - Dempsey, Paddy C.
AU - Lacy, Kathleen E.
AU - Dunstan, David W.
PY - 2018/3
Y1 - 2018/3
N2 - Objectives: To explore the impact of uninterrupted sitting versus sitting with resistance-type activity breaks on adolescents' postprandial glucose responses while consuming a diet varying in energy. Design: Cross-over randomised trial. Methods: Thirteen healthy participants (16.4. ±. 1.3. years) completed a four-treatment cross-over trial: (1) uninterrupted sitting + high-energy diet; (2) sitting with breaks + high-energy diet; (3) uninterrupted sitting + standard-energy diet; and (4) sitting with breaks + standard-energy diet. For all four conditions, two identical meals were consumed; at 0. h and 3. h. A continuous glucose monitoring system (CGM) recorded interstitial glucose concentrations every five minutes. Linear mixed models examined differences in glucose positive incremental area under the curve (iAUC) and total AUC between the sitting and diet conditions for the first meal, second meal and entire trial period. Results: Compared to the uninterrupted sitting conditions, the breaks condition elicited a 36.0. mmol/L/h (95%CI 6.6-65.5) and 35.9. mmol/L/h (95%CI 6.6-65.5) lower iAUC response after the first and second meal, respectively, but not for the entire trial period or for total AUC. Compared to the standard-energy diet, the high-energy diet elicited a 55.0. mmol/L/h (95%CI 25.8-84.2) and 75.7. mmol/L/h (95%CI 8.6-142.7) higher iAUC response after the first meal and entire trial, respectively. Similar response to the high-energy diet were observed for total AUC. Conclusions: According to iAUC, interrupting sitting had a significant effect on lowering postprandial glucose for both dietary conditions, however, it was not significant when examining total AUC. Larger studies are needed to confirm these findings. Clinical Trial Registration Number: ACTRN12615001145594.
AB - Objectives: To explore the impact of uninterrupted sitting versus sitting with resistance-type activity breaks on adolescents' postprandial glucose responses while consuming a diet varying in energy. Design: Cross-over randomised trial. Methods: Thirteen healthy participants (16.4. ±. 1.3. years) completed a four-treatment cross-over trial: (1) uninterrupted sitting + high-energy diet; (2) sitting with breaks + high-energy diet; (3) uninterrupted sitting + standard-energy diet; and (4) sitting with breaks + standard-energy diet. For all four conditions, two identical meals were consumed; at 0. h and 3. h. A continuous glucose monitoring system (CGM) recorded interstitial glucose concentrations every five minutes. Linear mixed models examined differences in glucose positive incremental area under the curve (iAUC) and total AUC between the sitting and diet conditions for the first meal, second meal and entire trial period. Results: Compared to the uninterrupted sitting conditions, the breaks condition elicited a 36.0. mmol/L/h (95%CI 6.6-65.5) and 35.9. mmol/L/h (95%CI 6.6-65.5) lower iAUC response after the first and second meal, respectively, but not for the entire trial period or for total AUC. Compared to the standard-energy diet, the high-energy diet elicited a 55.0. mmol/L/h (95%CI 25.8-84.2) and 75.7. mmol/L/h (95%CI 8.6-142.7) higher iAUC response after the first meal and entire trial, respectively. Similar response to the high-energy diet were observed for total AUC. Conclusions: According to iAUC, interrupting sitting had a significant effect on lowering postprandial glucose for both dietary conditions, however, it was not significant when examining total AUC. Larger studies are needed to confirm these findings. Clinical Trial Registration Number: ACTRN12615001145594.
KW - Adolescents
KW - Blood glucose
KW - Continuous glucose monitor
KW - Diet
KW - Sedentary lifestyle
UR - http://www.scopus.com/inward/record.url?scp=85020821384&partnerID=8YFLogxK
U2 - 10.1016/j.jsams.2017.06.002
DO - 10.1016/j.jsams.2017.06.002
M3 - Article
AN - SCOPUS:85020821384
SN - 1440-2440
VL - 21
SP - 280
EP - 285
JO - Journal of Science and Medicine in Sport
JF - Journal of Science and Medicine in Sport
IS - 3
ER -