Effects of airborne metals on lung function in inner Mongolian schoolchildren

OBJECTIVES:: To evaluate the effects of particles and their components on lung function. METHODS:: A panel study was conducted on 107 primary schoolchildren. The peak expiratory flow rate (PEFR) for each subject was measured three times a day for 40 days continuously. Particulate air concentrations were measured every day. The concentrations of Pb, Ni, Fe, Mn, Cr, As, Cd, and Zn in particles were measured. Linear mixed-effect models were used to estimate the associations between particles, metal elements, and PEFR. RESULTS:: We found that the increase in particles in air was associated with a significant reduction in PEFR. Its effects lasted 2 to 5 days. Pb, Ni, Fe, Mn, and Cr in particles also reduced PEFR. As and Cd increased PEFR. Zn showed inconstant effects on PEFR. CONCLUSION:: This study suggested that most metal components in particles have negative effects on children's lung function.