Effectivity of ventilation by measuring expired CO2 and RIP during stabilisation of preterm infants at birth

Jeroen J van Vonderen, Gianluca Lista, Francesco Cavigioli, Stuart Brian Hooper, Arjan B Te Pas

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24 Citations (Scopus)


To measure tidal volume, plethysmography changes and gas exchange during respiratory support at birth. DESIGN: The following parameters were measured: (1) expired tidal volumes (Vte (mL/kg)) using respiratory function monitoring, (2) changes in plethysmography (AU/kg) per breath using respiratory inductance plethysmography (bands placed around rib cage (RC) and abdomen (AB)) and (3) expired CO2 (ECO2) levels using a volumetric CO2 monitor. For respiratory support, a T-piece resuscitator and facemask were used with peak inspiratory pressure (PIP) 25 cm H2O and positive end expiratory pressure 5 cm H2O. Data were analysed during the sustained inflation (SI), positive pressure ventilation (PPV) and breathing on continuous positive airway pressure (CPAP). SETTING: The delivery rooms of the Leiden University Medical Center, Leiden, and V. Buzzi, Milan. PATIENTS: 15 preterm infants with a gestational age 28 (27-31) weeks and a birth weight of 1080 (994-1300) g. RESULTS: Vte for PPV inflations, PPV inflations with breathing and spontaneous breathing were significantly different (4.4 (2.5-8.6) vs 8.8 (5.7-11.4) vs 5.7 (3.3-9.8); p
Original languageEnglish
Pages (from-to)F514 - F518
Number of pages5
JournalArchives of Disease in Childhood: Fetal and Neonatal Edition
Issue number6
Publication statusPublished - 2015

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