Effectiveness of vertebroplasty using individual patient data from two randomised placebo controlled trials: Meta-analysis

Margaret Staples; David Kallmes; Bryan Comstock; Jeffrey Jarvik; Richard Harry Osborne; Patrick J Heagerty; Rachelle Buchbinder

doi:10.1136/bmj.d3952

Effectiveness of vertebroplasty using individual patient data from two randomised placebo controlled trials: Meta-analysis

Margaret Staples, David Kallmes, Bryan Comstock, Jeffrey Jarvik, Richard Harry Osborne, Patrick J Heagerty, Rachelle Buchbinder

Epidemiology and Preventive Medicine Alfred Hospital

Research output: Contribution to journal › Article › Research › peer-review

93 Citations (Scopus)

Abstract

Objective To determine whether vertebroplasty is more effective than placebo for patients with pain of recent onset (a??6 weeks) or severe pain (score a?Y8 on 0-10 numerical rating scale). Design Meta-analysis of combined individual patient level data. Setting Two multicentred randomised controlled trials of vertebroplasty; one based in Australia, the other in the United States.

Original language	English
Pages (from-to)	1 - 11
Number of pages	11
Journal	BMJ
Volume	343
Issue number	Art. No: d3952
DOIs	https://doi.org/10.1136/bmj.d3952
Publication status	Published - 2011

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10.1136/bmj.d3952

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Cite this

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abstract = "Objective To determine whether vertebroplasty is more effective than placebo for patients with pain of recent onset (a??6 weeks) or severe pain (score a?Y8 on 0-10 numerical rating scale). Design Meta-analysis of combined individual patient level data. Setting Two multicentred randomised controlled trials of vertebroplasty; one based in Australia, the other in the United States.",

author = "Margaret Staples and David Kallmes and Bryan Comstock and Jeffrey Jarvik and Osborne, {Richard Harry} and Heagerty, {Patrick J} and Rachelle Buchbinder",

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Effectiveness of vertebroplasty using individual patient data from two randomised placebo controlled trials: Meta-analysis. / Staples, Margaret; Kallmes, David; Comstock, Bryan; Jarvik, Jeffrey; Osborne, Richard Harry; Heagerty, Patrick J; Buchbinder, Rachelle.

In: BMJ, Vol. 343, No. Art. No: d3952, 2011, p. 1 - 11.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Heagerty, Patrick J

AU - Buchbinder, Rachelle

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AB - Objective To determine whether vertebroplasty is more effective than placebo for patients with pain of recent onset (a??6 weeks) or severe pain (score a?Y8 on 0-10 numerical rating scale). Design Meta-analysis of combined individual patient level data. Setting Two multicentred randomised controlled trials of vertebroplasty; one based in Australia, the other in the United States.

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