Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial

David W Johnson; Muh Geot Wong; Bruce A Cooper; Pauline Branley; Liliana Bulfone; John F Collins; Jonathan C Craig; Margaret Fraenkel; Anthony H Harris; Joan Kesselhut; Jing Jing Li; Grant Luxton; Andrew Pilmore; David J Tiller; David CH Harris; Carol A Pollock

doi:10.3747/pdi.2012.00046

Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial

David W Johnson, Muh Geot Wong, Bruce A Cooper, Pauline Branley, Liliana Bulfone, John F Collins, Jonathan C Craig, Margaret Fraenkel, Anthony H Harris, Joan Kesselhut, Jing Jing Li, Grant Luxton, Andrew Pilmore, David J Tiller, David CH Harris, Carol A Pollock

Centre for Health Economics

Research output: Contribution to journal › Article › Research › peer-review

33 Citations (Scopus)

Abstract

Since the mid-1990s, early dialysis initiation has dramatically increased in many countries. The Initiating Dialysis Early and Late (IDEAL) study demonstrated that, compared with late initiation, planned early initiation of dialysis was associated with comparable clinical outcomes and increased health care costs. Because residual renal function is a key determinant of outcome and is better preserved with peritoneal dialysis (PD), the present pre-specified subgroup analysis of the IDEAL trial examined the effects of early-compared with late-start dialysis on clinical outcomes in patients whose planned therapy at the time of randomization was PD.

Original language	English
Pages (from-to)	595 - 604
Number of pages	10
Journal	Peritoneal Dialysis International
Volume	32
Issue number	6
DOIs	https://doi.org/10.3747/pdi.2012.00046
Publication status	Published - 2012

Access to Document

10.3747/pdi.2012.00046

Cite this

Johnson, D. W., Wong, M. G., Cooper, B. A., Branley, P., Bulfone, L., Collins, J. F., Craig, J. C., Fraenkel, M., Harris, A. H., Kesselhut, J., Li, J. J., Luxton, G., Pilmore, A., Tiller, D. J., Harris, D. CH., & Pollock, C. A. (2012). Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial. Peritoneal Dialysis International, 32(6), 595 - 604. https://doi.org/10.3747/pdi.2012.00046

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abstract = "Since the mid-1990s, early dialysis initiation has dramatically increased in many countries. The Initiating Dialysis Early and Late (IDEAL) study demonstrated that, compared with late initiation, planned early initiation of dialysis was associated with comparable clinical outcomes and increased health care costs. Because residual renal function is a key determinant of outcome and is better preserved with peritoneal dialysis (PD), the present pre-specified subgroup analysis of the IDEAL trial examined the effects of early-compared with late-start dialysis on clinical outcomes in patients whose planned therapy at the time of randomization was PD.",

author = "Johnson, {David W} and Wong, {Muh Geot} and Cooper, {Bruce A} and Pauline Branley and Liliana Bulfone and Collins, {John F} and Craig, {Jonathan C} and Margaret Fraenkel and Harris, {Anthony H} and Joan Kesselhut and Li, {Jing Jing} and Grant Luxton and Andrew Pilmore and Tiller, {David J} and Harris, {David CH} and Pollock, {Carol A}",

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language = "English",

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Johnson, DW, Wong, MG, Cooper, BA, Branley, P, Bulfone, L, Collins, JF, Craig, JC, Fraenkel, M, Harris, AH, Kesselhut, J, Li, JJ, Luxton, G, Pilmore, A, Tiller, DJ, Harris, DCH & Pollock, CA 2012, 'Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial', Peritoneal Dialysis International, vol. 32, no. 6, pp. 595 - 604. https://doi.org/10.3747/pdi.2012.00046

TY - JOUR

T1 - Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial

AU - Johnson, David W

AU - Wong, Muh Geot

AU - Cooper, Bruce A

AU - Branley, Pauline

AU - Bulfone, Liliana

AU - Collins, John F

AU - Craig, Jonathan C

AU - Fraenkel, Margaret

AU - Harris, Anthony H

AU - Kesselhut, Joan

AU - Li, Jing Jing

AU - Luxton, Grant

AU - Pilmore, Andrew

AU - Tiller, David J

AU - Harris, David CH

AU - Pollock, Carol A

PY - 2012

Y1 - 2012

N2 - Since the mid-1990s, early dialysis initiation has dramatically increased in many countries. The Initiating Dialysis Early and Late (IDEAL) study demonstrated that, compared with late initiation, planned early initiation of dialysis was associated with comparable clinical outcomes and increased health care costs. Because residual renal function is a key determinant of outcome and is better preserved with peritoneal dialysis (PD), the present pre-specified subgroup analysis of the IDEAL trial examined the effects of early-compared with late-start dialysis on clinical outcomes in patients whose planned therapy at the time of randomization was PD.

AB - Since the mid-1990s, early dialysis initiation has dramatically increased in many countries. The Initiating Dialysis Early and Late (IDEAL) study demonstrated that, compared with late initiation, planned early initiation of dialysis was associated with comparable clinical outcomes and increased health care costs. Because residual renal function is a key determinant of outcome and is better preserved with peritoneal dialysis (PD), the present pre-specified subgroup analysis of the IDEAL trial examined the effects of early-compared with late-start dialysis on clinical outcomes in patients whose planned therapy at the time of randomization was PD.

U2 - 10.3747/pdi.2012.00046

DO - 10.3747/pdi.2012.00046

M3 - Article

SN - 0896-8608

VL - 32

SP - 595

EP - 604

JO - Peritoneal Dialysis International

JF - Peritoneal Dialysis International

IS - 6

ER -