Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial

David W Johnson, Muh Geot Wong, Bruce A Cooper, Pauline Branley, Liliana Bulfone, John F Collins, Jonathan C Craig, Margaret Fraenkel, Anthony H Harris, Joan Kesselhut, Jing Jing Li, Grant Luxton, Andrew Pilmore, David J Tiller, David CH Harris, Carol A Pollock

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Abstract

Since the mid-1990s, early dialysis initiation has dramatically increased in many countries. The Initiating Dialysis Early and Late (IDEAL) study demonstrated that, compared with late initiation, planned early initiation of dialysis was associated with comparable clinical outcomes and increased health care costs. Because residual renal function is a key determinant of outcome and is better preserved with peritoneal dialysis (PD), the present pre-specified subgroup analysis of the IDEAL trial examined the effects of early-compared with late-start dialysis on clinical outcomes in patients whose planned therapy at the time of randomization was PD.
Original languageEnglish
Pages (from-to)595 - 604
Number of pages10
JournalPeritoneal Dialysis International
Volume32
Issue number6
DOIs
Publication statusPublished - 2012

Cite this

Johnson, D. W., Wong, M. G., Cooper, B. A., Branley, P., Bulfone, L., Collins, J. F., Craig, J. C., Fraenkel, M., Harris, A. H., Kesselhut, J., Li, J. J., Luxton, G., Pilmore, A., Tiller, D. J., Harris, D. CH., & Pollock, C. A. (2012). Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial. Peritoneal Dialysis International, 32(6), 595 - 604. https://doi.org/10.3747/pdi.2012.00046