Effect of sustained inflation length on establishing functional residual capacity at birth in ventilated premature rabbits

Arjan B Te Pas, Melissa Li-Lian Siew, Megan Jane Wallace, Marcus John Kitchen, Andreas Fouras, Robert Lewis, Naoto Yagi, Kentaro Uesugi, Susan Donath, Peter G Davis, Colin J Morley, Stuart Brian Hooper

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The effect of inflation length on lung aeration pattern, tidal volumes and functional residual capacity (FRC) immediately after birth was investigated. Preterm rabbits (28 days), randomized into 4 groups, received a 1, 5, 10, or 20 sec inflation (SI) followed by ventilation with 5 cmH2O end-expiratory pressure. Gas volumes were measured by plethysmography and uniformity of lung aeration by phase contrast X-ray imaging for 7 minutes. The first inspiratory volume significantly (p
Original languageEnglish
Pages (from-to)295 - 300
Number of pages6
JournalPediatric Research
Volume66
Issue number3
DOIs
Publication statusPublished - 2009

Cite this

Te Pas, Arjan B ; Siew, Melissa Li-Lian ; Wallace, Megan Jane ; Kitchen, Marcus John ; Fouras, Andreas ; Lewis, Robert ; Yagi, Naoto ; Uesugi, Kentaro ; Donath, Susan ; Davis, Peter G ; Morley, Colin J ; Hooper, Stuart Brian. / Effect of sustained inflation length on establishing functional residual capacity at birth in ventilated premature rabbits. In: Pediatric Research. 2009 ; Vol. 66, No. 3. pp. 295 - 300.
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Effect of sustained inflation length on establishing functional residual capacity at birth in ventilated premature rabbits. / Te Pas, Arjan B; Siew, Melissa Li-Lian; Wallace, Megan Jane; Kitchen, Marcus John; Fouras, Andreas; Lewis, Robert; Yagi, Naoto; Uesugi, Kentaro; Donath, Susan; Davis, Peter G; Morley, Colin J; Hooper, Stuart Brian.

In: Pediatric Research, Vol. 66, No. 3, 2009, p. 295 - 300.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Siew, Melissa Li-Lian

AU - Wallace, Megan Jane

AU - Kitchen, Marcus John

AU - Fouras, Andreas

AU - Lewis, Robert

AU - Yagi, Naoto

AU - Uesugi, Kentaro

AU - Donath, Susan

AU - Davis, Peter G

AU - Morley, Colin J

AU - Hooper, Stuart Brian

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AB - The effect of inflation length on lung aeration pattern, tidal volumes and functional residual capacity (FRC) immediately after birth was investigated. Preterm rabbits (28 days), randomized into 4 groups, received a 1, 5, 10, or 20 sec inflation (SI) followed by ventilation with 5 cmH2O end-expiratory pressure. Gas volumes were measured by plethysmography and uniformity of lung aeration by phase contrast X-ray imaging for 7 minutes. The first inspiratory volume significantly (p

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