TY - JOUR
T1 - Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study
AU - Mahfoud, Felix
AU - Schlaich, Markus
AU - Kindermann, Ingrid
AU - Ukena, Christian
AU - Cremers, Bodo
AU - Brandt, Mathias
AU - Hoppe, Uta
AU - Vonend, Oliver
AU - Rump, Lars
AU - Sobotka, Paul
AU - Krum, Henry
AU - Esler, Murray
AU - Bohm, Michael
PY - 2011
Y1 - 2011
N2 - Methods and Results
We enrolled 50 patients with therapy-resistant hypertension. Thirty-seven patients underwent bilateral catheter-based renal denervation, and 13 patients were assigned to a control group. Systolic and diastolic blood pressures, fasting glucose, insulin, C peptide, hemoglobin A1c, calculated insulin sensitivity (homeostasis model assessmenta??insulin resistance), and glucose levels during oral glucose tolerance test were measured before and 1 and 3 months after treatment. Mean office blood pressure at baseline was 178/96A?3/2 mm Hg. At 1 and 3 months, office blood pressure was reduced by a??28/a??10 mm Hg (P
AB - Methods and Results
We enrolled 50 patients with therapy-resistant hypertension. Thirty-seven patients underwent bilateral catheter-based renal denervation, and 13 patients were assigned to a control group. Systolic and diastolic blood pressures, fasting glucose, insulin, C peptide, hemoglobin A1c, calculated insulin sensitivity (homeostasis model assessmenta??insulin resistance), and glucose levels during oral glucose tolerance test were measured before and 1 and 3 months after treatment. Mean office blood pressure at baseline was 178/96A?3/2 mm Hg. At 1 and 3 months, office blood pressure was reduced by a??28/a??10 mm Hg (P
UR - http://circ.ahajournals.org/cgi/content/abstract/123/18/1940
U2 - 10.1161/CIRCULATIONAHA.110.991869
DO - 10.1161/CIRCULATIONAHA.110.991869
M3 - Article
SN - 0009-7322
VL - 123
SP - 1940
EP - 1946
JO - Circulation
JF - Circulation
IS - 18
ER -