TY - JOUR
T1 - Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus
AU - Ejtahed, H. S.
AU - Mohtadi-Nia, J.
AU - Homayouni-Rad, A.
AU - Niafar, M.
AU - Asghari-Jafarabadi, M.
AU - Mofid, V.
AU - Akbarian-Moghari, A.
N1 - Funding Information:
The present study was supported by a grant (no. 5/4/3229) from The Research Vice-Chancellor of Tabriz University of Medical Sciences (Tabriz, Iran). The authors thank the Iran Dairy Industries Co. (Tehran) for supplying the probiotic and conventional yogurts.
PY - 2011/7
Y1 - 2011/7
N2 - The purpose of this study was to investigate the effects of probiotic and conventional yogurt on the lipid profile in type 2 diabetic people. In a randomized double-blind controlled trial, 60 people (23 males and 37 females) with type 2 diabetes and low-density lipoprotein cholesterol (LDL-C) greater than 2.6 mmol/L were assigned to 2 groups. Participants consumed daily 300. g of probiotic yogurt containing Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 or 300. g of conventional yogurt for 6 wk. Fasting blood samples, anthropometric measurements and 3-d, 24-h dietary recalls were collected at the baseline and at the end of the trial. Probiotic yogurt consumption caused a 4.54% decrease in total cholesterol and a 7.45% decrease in LDL-C compared with the control group. No significant changes from baseline were shown in triglyceride and high-density lipoprotein cholesterol (HDL-C) in the probiotic group. The total cholesterol:HDL-C ratio and LDL-C:HDL-C ratio as atherogenic indices significantly decreased in the probiotic group compared with the control group. Probiotic yogurt improved total cholesterol and LDL-C concentrations in type 2 diabetic people and may contribute to the improvement of cardiovascular disease risk factors.
AB - The purpose of this study was to investigate the effects of probiotic and conventional yogurt on the lipid profile in type 2 diabetic people. In a randomized double-blind controlled trial, 60 people (23 males and 37 females) with type 2 diabetes and low-density lipoprotein cholesterol (LDL-C) greater than 2.6 mmol/L were assigned to 2 groups. Participants consumed daily 300. g of probiotic yogurt containing Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 or 300. g of conventional yogurt for 6 wk. Fasting blood samples, anthropometric measurements and 3-d, 24-h dietary recalls were collected at the baseline and at the end of the trial. Probiotic yogurt consumption caused a 4.54% decrease in total cholesterol and a 7.45% decrease in LDL-C compared with the control group. No significant changes from baseline were shown in triglyceride and high-density lipoprotein cholesterol (HDL-C) in the probiotic group. The total cholesterol:HDL-C ratio and LDL-C:HDL-C ratio as atherogenic indices significantly decreased in the probiotic group compared with the control group. Probiotic yogurt improved total cholesterol and LDL-C concentrations in type 2 diabetic people and may contribute to the improvement of cardiovascular disease risk factors.
KW - Lipid profile
KW - Probiotic yogurt
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=79959367309&partnerID=8YFLogxK
U2 - 10.3168/jds.2010-4128
DO - 10.3168/jds.2010-4128
M3 - Article
C2 - 21700013
AN - SCOPUS:79959367309
SN - 0022-0302
VL - 94
SP - 3288
EP - 3294
JO - Journal of Dairy Science
JF - Journal of Dairy Science
IS - 7
ER -
