Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials

Hiddo J Lambers Heerspink, Toshiharu Ninomiya, Sophia Zoungas, Dick de Zeeuw, Diederick E Grobbee, Meg J Jardine, Martin Gallagher, Matthew A Roberts, Alan Cass, Bruce Neal, Vlado Perkovic

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    Abstract

    Patients undergoing dialysis have a substantially increased risk of cardiovascular mortality and morbidity. Although several trials have shown the cardiovascular benefits of lowering blood pressure in the general population, there is uncertainty about the efficacy and tolerability of reducing blood pressure in patients on dialysis. We did a systematic review and meta-analysis to assess the effect of blood pressure lowering in patients on dialysis
    Original languageEnglish
    Pages (from-to)1009 - 1015
    Number of pages7
    JournalThe Lancet
    Volume373
    Issue number9668
    DOIs
    Publication statusPublished - 2009

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