Exposing pregnant sheep to an ambient temperature of 43 ± 1°C for 8 h was associated with a 1-1.5°C increase of maternal and fetal core temperatures, and a 11-fold and 3-5 fold increase in maternal and fetal plasma prolactin concentrations respectively. Hyperthermia did not change maternal or fetal plasma cortisol concentrations. We conclude that maternal and fetal hyperprolactinaemia may occur in late pregnancy during hyperthermic conditions and that the increase in fetal plasma prolactin is due to either increased secretion or decreased metabolic clearance of prolactin in the feto-placental compartment.
|Number of pages||5|
|Journal||Journal of Developmental Physiology|
|Publication status||Published - 19 Nov 1990|