Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations

Background: Structured lipids are being incorporated into foods tO reduce their energy value. One such lipid is rich in stearic acid. Objective: The objective of this study was tO compare the effects on plasma lipids of a stearic acid-rich triacylglycerol and a fat rich in palmitic acid in hypercholesterolemic subjects. Design: Fifteen subjects with an average plasma cholesterol concentration of 6.13 ± 0.80 mmol/L initially ate a low- fat diet for 2 wk (run-in period), followed in random order and blinded fashion by 2 high-fat diets (for 5 wk each) containing foods derived froth margarines rich either in palmitic acid or in the structured, stearic acid- rich triacylglycerol. Results: Plasma cholesterol concentrations with the low-fat, the stearic acid-rich, and the palmitic acid-rich diets were not significantly different (5.35 ± 0.83, 5.41 ± 0.78, and 5.52 ± 0.68 mmol/L, respectively) but were significantly lower (P < 0.001) than those measured during the habitual diet period (ie, 2 wk before the study began). Neither HDL cholesterol nor plasma triacylglycerol differed significantly among the 3 study diets. Conclusion: A similar increase in the intake of stearic and palmitic acids (differing by ≃5% of total energy) to ensure a high fat intake resulted in plasma total and LDL-cholesterol concentrations that did not differ significantly from concentrations measured during a period of low- fat intake.