Ecological drivers of virus evolution: Astrovirus as a case study

Ian H. Mendenhall, Gavin J. D. Smith, Dhanasekaran Vijaykrishna

Research output: Contribution to journalReview ArticleOtherpeer-review

30 Citations (Scopus)


Although RNA viruses exhibit a high frequency of host jumps, major differences exist among the different virus families. Astroviruses infect a wide range of hosts, affecting both public health systems and economic production chains. Here we delineate the ecological and adaptive processes that drive the cross-species transmission of astroviruses. We observe that distinct transmission zones determine the prevailing astrovirus host and virus diversity, which in turn suggests that no single host group (e.g., bats) can be the natural reservoir, as illustrated through our phylogenetic analysis.

Original languageEnglish
Pages (from-to)6978-6981
Number of pages4
JournalJournal of Virology
Issue number14
Publication statusPublished - Jul 2015
Externally publishedYes

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