Early skin and challenge testing after rocuronium anaphylaxis

E. M. Schulberg, A. R. Webb, H. Kolawole

Research output: Contribution to journalArticleOtherpeer-review

17 Citations (Scopus)


We present a case of early skin and challenge testing in a patient following severe anaphylaxis to rocuronium. The patient presented for semi-elective laparoscopic cholecystectomy and developed anaphylaxis with severe cardiovascular collapse after induction of anaesthesia. Surgery was cancelled but was considered necessary before the recommended four to six weeks for formal allergy testing. Limited skin and challenge testing was performed to rocuronium and cisatracurium while the patient was in the intensive care unit to identify a safe neuromuscular blocking drug for subsequent early surgery. The subsequent surgery, 48 hours after the initial reaction, was uneventful. The case highlights the difficulties when anaesthetising patients with recent anaphylaxis who have not yet had formal allergy testing and presents a potential management strategy involving early skin testing.

Original languageEnglish
Pages (from-to)425-427
Number of pages3
JournalAnaesthesia and Intensive Care
Issue number3
Publication statusPublished - May 2016
Externally publishedYes


  • Anaesthesia
  • Anaphylaxis
  • Neuromuscular blocking agents
  • Remifentanil
  • Rocuronium

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