TY - JOUR
T1 - Early Pharmacologic Venous Thromboembolism Prophylaxis after Splenic Artery Embolization Is Not Associated with an Increased Risk of Rebleed
AU - Clements, Warren
AU - Nandurkar, Rohan
AU - Dyer, Jessamy
AU - Mathew, Joseph
N1 - Funding Information:
The authors acknowledge all the staff in both the Department of Radiology and Department of Trauma at The Alfred Hospital. In addition, the authors acknowledge the National Trauma Research Institute and the Alfred Trauma Registry. Furthermore, the authors acknowledge the assistance of Dr. Tim Joseph, Dr. Jim Koukounaras, Associate Prof. Gerard Goh, Dr. Tuan Phan, Dr. Heather Moriarty, Dr. Katherine Martin, and Dr. Shelley Chapman.
Publisher Copyright:
© 2021 SIR
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/8/1
Y1 - 2021/8/1
N2 - Venous thromboembolism (VTE) prophylaxis in the setting of blunt traumatic visceral injury remains controversial. A total of 181 patients underwent splenic artery embolization (SAE) and began pharmacologic VTE prophylaxis at a median time of 59.5 hours (interquartile range, 46 hours). Six patients required splenectomy for rebleed. Fifty-one patients underwent SAE but did not receive anticoagulation therapy since they were considered low risk for VTE, and no splenectomies were performed (P = 1). Multivariate analysis showed no increased risk of need for splenectomy after beginning anticoagulation within 24 hours after SAE (P =.441). This study suggests that patients found to be at a high VTE risk should be considered for thromboprophylaxis within 24 hours after SAE.
AB - Venous thromboembolism (VTE) prophylaxis in the setting of blunt traumatic visceral injury remains controversial. A total of 181 patients underwent splenic artery embolization (SAE) and began pharmacologic VTE prophylaxis at a median time of 59.5 hours (interquartile range, 46 hours). Six patients required splenectomy for rebleed. Fifty-one patients underwent SAE but did not receive anticoagulation therapy since they were considered low risk for VTE, and no splenectomies were performed (P = 1). Multivariate analysis showed no increased risk of need for splenectomy after beginning anticoagulation within 24 hours after SAE (P =.441). This study suggests that patients found to be at a high VTE risk should be considered for thromboprophylaxis within 24 hours after SAE.
UR - http://www.scopus.com/inward/record.url?scp=85106270355&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2021.03.542
DO - 10.1016/j.jvir.2021.03.542
M3 - Article
C2 - 33831564
AN - SCOPUS:85106270355
VL - 32
SP - 1158
EP - 1163
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
SN - 1051-0443
IS - 8
ER -