TY - JOUR
T1 - Early pancreas allograft thrombosis
AU - Ramessur, Sharmila
AU - Kanellis, John
AU - Polkinghorne, Kevan R
AU - Saunder, Alan Charles
AU - Mulley, William
PY - 2013
Y1 - 2013
N2 - OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p
AB - OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p
UR - http://www.ncbi.nlm.nih.gov/pubmed/23495654
U2 - 10.1111/ctr.12105
DO - 10.1111/ctr.12105
M3 - Article
VL - 27
SP - 410
EP - 416
JO - Clinical Transplantation
JF - Clinical Transplantation
SN - 1399-0012
IS - 3
ER -