Early pancreas allograft thrombosis

Sharmila Ramessur, John Kanellis, Kevan R Polkinghorne, Alan Charles Saunder, William Mulley

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20 Citations (Scopus)


OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p
Original languageEnglish
Pages (from-to)410 - 416
Number of pages7
JournalClinical Transplantation
Issue number3
Publication statusPublished - 2013

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