Early pancreas allograft thrombosis

Research output: Contribution to journalArticleResearchpeer-review

Abstract

OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p
Original languageEnglish
Pages (from-to)410 - 416
Number of pages7
JournalClinical Transplantation
Volume27
Issue number3
DOIs
Publication statusPublished - 2013

Cite this

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title = "Early pancreas allograft thrombosis",
abstract = "OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p",
author = "Sharmila Ramessur and John Kanellis and Polkinghorne, {Kevan R} and Saunder, {Alan Charles} and William Mulley",
year = "2013",
doi = "10.1111/ctr.12105",
language = "English",
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pages = "410 -- 416",
journal = "Clinical Transplantation",
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Early pancreas allograft thrombosis. / Ramessur, Sharmila; Kanellis, John; Polkinghorne, Kevan R; Saunder, Alan Charles; Mulley, William.

In: Clinical Transplantation, Vol. 27, No. 3, 2013, p. 410 - 416.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Early pancreas allograft thrombosis

AU - Ramessur, Sharmila

AU - Kanellis, John

AU - Polkinghorne, Kevan R

AU - Saunder, Alan Charles

AU - Mulley, William

PY - 2013

Y1 - 2013

N2 - OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p

AB - OBJECTIVES: To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological cause of early pancreatic allograft failure. Multiple risk factors have been postulated. We hypothesized that recipient perioperative hypotension was a major risk factor and evaluated the correlation of this and other parameters with EPAT. METHODS: We retrospectively reviewed the records of the 118 patients who received a pancreatic allograft at our center between October 1992 and January 2010. Multiple donor and recipient parameters were analyzed as associates of EPAT by univariate and multivariate analysis. RESULTS: There were 12 episodes of EPAT, resulting in an incidence of 10.2 . On univariate analysis, EPAT was associated with perioperative hypotension, vasopressor use, and neuropathy in the recipient (p

UR - http://www.ncbi.nlm.nih.gov/pubmed/23495654

U2 - 10.1111/ctr.12105

DO - 10.1111/ctr.12105

M3 - Article

VL - 27

SP - 410

EP - 416

JO - Clinical Transplantation

JF - Clinical Transplantation

SN - 0902-0063

IS - 3

ER -