Early Outcomes of Sutureless Aortic Valve Replacement With the Perceval S Bioprosthesis

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Sutureless aortic valve replacement (SU-AVR)offers an alternative to traditional aortic valve replacement (AVR)and is becoming widely performed in many hospitals. The aim of the current study was to evaluate the early experience in SU-AVR with the Perceval S bioprosthesis at Monash Medical Centre. Methods: Fifty-two (52)patients who underwent SU-AVR were retrospectively analysed (mean age: 74.8 ± 6.5 years). Data regarding preoperative and operative details, hospital stay, postoperative outcomes within 30 days after surgery, re-admissions and longer term echocardiographic data were collected from the relevant hospital databases. Results: In isolated SU-AVR, the mean aortic cross-clamp and cardiopulmonary bypass times were 48.8 and 67.8 minutes, respectively. There were no deaths within 30 days after surgery. Rhythm disturbances developed in 46.2% of patients, with atrial fibrillation (32.7%)and heart block (9.6%)being most common. Mean and peak transaortic gradients reduced from 46.2 and 77.9 mmHg preoperatively, to 10.7 and 19.7 mmHg at 12 months postoperatively, respectively. Conclusions: The absence of early mortality and the satisfactory clinical and haemodynamic results demonstrated the overall safety and efficacy of the Perceval S valve. Although sutureless valves seem to be a promising alternative to traditional sutured valves, the high rate of new postoperative rhythm disturbances, particularly heart block, is potentially a concern with SU-AVR.

Original languageEnglish
Pages (from-to)970-976
Number of pages7
JournalHeart Lung and Circulation
Volume28
Issue number6
DOIs
Publication statusPublished - 1 Jun 2019

Keywords

  • Early experience
  • Perceval S
  • Sutureless aortic valve replacement

Cite this

@article{9810673228b546ef8e53c69b0695ef17,
title = "Early Outcomes of Sutureless Aortic Valve Replacement With the Perceval S Bioprosthesis",
abstract = "Background: Sutureless aortic valve replacement (SU-AVR)offers an alternative to traditional aortic valve replacement (AVR)and is becoming widely performed in many hospitals. The aim of the current study was to evaluate the early experience in SU-AVR with the Perceval S bioprosthesis at Monash Medical Centre. Methods: Fifty-two (52)patients who underwent SU-AVR were retrospectively analysed (mean age: 74.8 ± 6.5 years). Data regarding preoperative and operative details, hospital stay, postoperative outcomes within 30 days after surgery, re-admissions and longer term echocardiographic data were collected from the relevant hospital databases. Results: In isolated SU-AVR, the mean aortic cross-clamp and cardiopulmonary bypass times were 48.8 and 67.8 minutes, respectively. There were no deaths within 30 days after surgery. Rhythm disturbances developed in 46.2{\%} of patients, with atrial fibrillation (32.7{\%})and heart block (9.6{\%})being most common. Mean and peak transaortic gradients reduced from 46.2 and 77.9 mmHg preoperatively, to 10.7 and 19.7 mmHg at 12 months postoperatively, respectively. Conclusions: The absence of early mortality and the satisfactory clinical and haemodynamic results demonstrated the overall safety and efficacy of the Perceval S valve. Although sutureless valves seem to be a promising alternative to traditional sutured valves, the high rate of new postoperative rhythm disturbances, particularly heart block, is potentially a concern with SU-AVR.",
keywords = "Early experience, Perceval S, Sutureless aortic valve replacement",
author = "Michael Kosasih and Almeida, {Aubrey A.} and Smith, {Julian A.}",
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Early Outcomes of Sutureless Aortic Valve Replacement With the Perceval S Bioprosthesis. / Kosasih, Michael; Almeida, Aubrey A.; Smith, Julian A.

In: Heart Lung and Circulation, Vol. 28, No. 6, 01.06.2019, p. 970-976.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Early Outcomes of Sutureless Aortic Valve Replacement With the Perceval S Bioprosthesis

AU - Kosasih, Michael

AU - Almeida, Aubrey A.

AU - Smith, Julian A.

PY - 2019/6/1

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N2 - Background: Sutureless aortic valve replacement (SU-AVR)offers an alternative to traditional aortic valve replacement (AVR)and is becoming widely performed in many hospitals. The aim of the current study was to evaluate the early experience in SU-AVR with the Perceval S bioprosthesis at Monash Medical Centre. Methods: Fifty-two (52)patients who underwent SU-AVR were retrospectively analysed (mean age: 74.8 ± 6.5 years). Data regarding preoperative and operative details, hospital stay, postoperative outcomes within 30 days after surgery, re-admissions and longer term echocardiographic data were collected from the relevant hospital databases. Results: In isolated SU-AVR, the mean aortic cross-clamp and cardiopulmonary bypass times were 48.8 and 67.8 minutes, respectively. There were no deaths within 30 days after surgery. Rhythm disturbances developed in 46.2% of patients, with atrial fibrillation (32.7%)and heart block (9.6%)being most common. Mean and peak transaortic gradients reduced from 46.2 and 77.9 mmHg preoperatively, to 10.7 and 19.7 mmHg at 12 months postoperatively, respectively. Conclusions: The absence of early mortality and the satisfactory clinical and haemodynamic results demonstrated the overall safety and efficacy of the Perceval S valve. Although sutureless valves seem to be a promising alternative to traditional sutured valves, the high rate of new postoperative rhythm disturbances, particularly heart block, is potentially a concern with SU-AVR.

AB - Background: Sutureless aortic valve replacement (SU-AVR)offers an alternative to traditional aortic valve replacement (AVR)and is becoming widely performed in many hospitals. The aim of the current study was to evaluate the early experience in SU-AVR with the Perceval S bioprosthesis at Monash Medical Centre. Methods: Fifty-two (52)patients who underwent SU-AVR were retrospectively analysed (mean age: 74.8 ± 6.5 years). Data regarding preoperative and operative details, hospital stay, postoperative outcomes within 30 days after surgery, re-admissions and longer term echocardiographic data were collected from the relevant hospital databases. Results: In isolated SU-AVR, the mean aortic cross-clamp and cardiopulmonary bypass times were 48.8 and 67.8 minutes, respectively. There were no deaths within 30 days after surgery. Rhythm disturbances developed in 46.2% of patients, with atrial fibrillation (32.7%)and heart block (9.6%)being most common. Mean and peak transaortic gradients reduced from 46.2 and 77.9 mmHg preoperatively, to 10.7 and 19.7 mmHg at 12 months postoperatively, respectively. Conclusions: The absence of early mortality and the satisfactory clinical and haemodynamic results demonstrated the overall safety and efficacy of the Perceval S valve. Although sutureless valves seem to be a promising alternative to traditional sutured valves, the high rate of new postoperative rhythm disturbances, particularly heart block, is potentially a concern with SU-AVR.

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