Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor

Sonia McCallum; Anthony Cambareri; Adam Odell; Sean Geary; Leonie Ashman

Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor

Sonia McCallum, Anthony Cambareri, Adam Odell, Sean Geary, Leonie Ashman

Health Systems Services & Policy

Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)

Abstract

Isoforms of the receptor tyrosine kinase, c-KIT, differ in the presence or absence of a GNNK tetrapeptide in the extracellular juxtamembrane region. When expressed in murine NIH3T3 cells, these isoforms of c-KIT showed differential activation of signaling pathways and proliferation in response to Stem Cell Factor.

Original language	English
Pages (from-to)	2572 - 2581
Number of pages	9
Journal	Cellular Signalling
Volume	19
Publication status	Published - 2007

Cite this

@article{26766fdf1cfd454a8eca14818dcc609a,

title = "Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor",

abstract = "Isoforms of the receptor tyrosine kinase, c-KIT, differ in the presence or absence of a GNNK tetrapeptide in the extracellular juxtamembrane region. When expressed in murine NIH3T3 cells, these isoforms of c-KIT showed differential activation of signaling pathways and proliferation in response to Stem Cell Factor.",

author = "Sonia McCallum and Anthony Cambareri and Adam Odell and Sean Geary and Leonie Ashman",

year = "2007",

language = "English",

volume = "19",

pages = "2572 -- 2581",

journal = "Cellular Signalling",

issn = "0898-6568",

publisher = "Elsevier",

}

TY - JOUR

T1 - Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor

AU - McCallum, Sonia

AU - Cambareri, Anthony

AU - Odell, Adam

AU - Geary, Sean

AU - Ashman, Leonie

PY - 2007

Y1 - 2007

N2 - Isoforms of the receptor tyrosine kinase, c-KIT, differ in the presence or absence of a GNNK tetrapeptide in the extracellular juxtamembrane region. When expressed in murine NIH3T3 cells, these isoforms of c-KIT showed differential activation of signaling pathways and proliferation in response to Stem Cell Factor.

AB - Isoforms of the receptor tyrosine kinase, c-KIT, differ in the presence or absence of a GNNK tetrapeptide in the extracellular juxtamembrane region. When expressed in murine NIH3T3 cells, these isoforms of c-KIT showed differential activation of signaling pathways and proliferation in response to Stem Cell Factor.

M3 - Article

SN - 0898-6568

VL - 19

SP - 2572

EP - 2581

JO - Cellular Signalling

JF - Cellular Signalling

ER -