Early-life telomere length predicts lifespan and lifetime reproductive success in a wild bird

Justin Ross Eastwood, Michelle L Hall, Niki Teunissen, Sjouke A Kingma, Nataly Hidalgo Aranzamendi, Marie Fan, Michael James Roast, Simon Verhulst, Anne Peters

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

Poor conditions during early development can initiate trade-offs that favour current survival at the expense of somatic maintenance and subsequently, future reproduction. However, the mechanisms that link early and late life-history are largely unknown. Recently it has been suggested that telomeres, the nucleoprotein structures at the terminal end of chromosomes, could link early-life conditions to lifespan and fitness. In wild purple-crowned fairy-wrens, we combined measurements of nestling telomere length (TL) with detailed life-history data to investigate whether early-life TL predicts fitness prospects. Our study differs from previous studies in the completeness of our fitness estimates in a highly philopatric population. The association between TL and survival was age-dependent with early-life TL having a positive effect on lifespan only among individuals that survived their first year. Early-life TL was not associated with the probability or age of gaining a breeding position. Interestingly, early-life TL was positively related to breeding duration, contribution to population growth and lifetime reproductive success because of their association with lifespan. Thus, early-life TL, which reflects growth, accumulated early-life stress and inherited TL, predicted fitness in birds that reached adulthood but not noticeably among fledglings. These findings suggest that a lack of investment in somatic maintenance during development particularly affects late life performance. This study demonstrates that factors in early-life are related to fitness prospects through lifespan, and suggests that the study of telomeres may provide insight into the underlying physiological mechanisms linking early- and late-life performance and trade-offs across a lifetime.

Original languageEnglish
Pages (from-to)1127-1137
Number of pages11
JournalMolecular Ecology
Volume28
Issue number5
DOIs
Publication statusPublished - 1 Mar 2019

Keywords

  • ageing
  • development
  • fitness
  • late-life
  • life-history
  • telomere
  • trade-offs

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