Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

Hemant Kulkarni; Weijing He; Koleka Mlisana; Edwina Wright; Lise Werner; John Castiblanco,; Rahul Dhanda; Tuan Le; Mathew J Dolan; Weihua Guan; Robin A Weiss; Robert A Clark; Salim S Abdool Karim; Sunil K Ahuja; Thumbi Ndung'u

doi:10.1093/cid/cir119

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

Hemant Kulkarni, Weijing He, Koleka Mlisana, Edwina Wright, Lise Werner, John Castiblanco,, Rahul Dhanda, Tuan Le, Mathew J Dolan, Weihua Guan, Robin A Weiss, Robert A Clark, Salim S Abdool Karim, Sunil K Ahuja, Thumbi Ndung'u

Research output: Contribution to journal › Article › Research › peer-review

54 Citations (Scopus)

Abstract

The triangular relationship among pre-seroconversion PBC counts, host genotypes, and risk of HIV acquisition was determined in a prospective cohort of black South African high-risk female sex workers. Twentyseven women had seroconversion during follow-up, and 115 remained HIV negative for 2 years, despite engaging in high-risk activity

Original language	English
Pages (from-to)	1248 - 1256
Number of pages	9
Journal	Clinical Infectious Diseases
Volume	52
Issue number	10
DOIs	https://doi.org/10.1093/cid/cir119
Publication status	Published - 2011
Externally published	Yes

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10.1093/cid/cir119

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Kulkarni, H., He, W., Mlisana, K., Wright, E., Werner, L., Castiblanco, J., Dhanda, R., Le, T., Dolan, M. J., Guan, W., Weiss, R. A., Clark, R. A., Abdool Karim, S. S., Ahuja, S. K., & Ndung'u, T. (2011). Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. Clinical Infectious Diseases, 52(10), 1248 - 1256. https://doi.org/10.1093/cid/cir119

Kulkarni, Hemant ; He, Weijing ; Mlisana, Koleka ; Wright, Edwina ; Werner, Lise ; Castiblanco, John ; Dhanda, Rahul ; Le, Tuan ; Dolan, Mathew J ; Guan, Weihua ; Weiss, Robin A ; Clark, Robert A ; Abdool Karim, Salim S ; Ahuja, Sunil K ; Ndung'u, Thumbi. / Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. In: Clinical Infectious Diseases. 2011 ; Vol. 52, No. 10. pp. 1248 - 1256.

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title = "Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women",

abstract = "The triangular relationship among pre-seroconversion PBC counts, host genotypes, and risk of HIV acquisition was determined in a prospective cohort of black South African high-risk female sex workers. Twentyseven women had seroconversion during follow-up, and 115 remained HIV negative for 2 years, despite engaging in high-risk activity",

author = "Hemant Kulkarni and Weijing He and Koleka Mlisana and Edwina Wright and Lise Werner and John Castiblanco, and Rahul Dhanda and Tuan Le and Dolan, {Mathew J} and Weihua Guan and Weiss, {Robin A} and Clark, {Robert A} and {Abdool Karim}, {Salim S} and Ahuja, {Sunil K} and Thumbi Ndung'u",

year = "2011",

doi = "10.1093/cid/cir119",

language = "English",

volume = "52",

pages = "1248 -- 1256",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

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Kulkarni, H, He, W, Mlisana, K, Wright, E, Werner, L, Castiblanco, J, Dhanda, R, Le, T, Dolan, MJ, Guan, W, Weiss, RA, Clark, RA, Abdool Karim, SS, Ahuja, SK & Ndung'u, T 2011, 'Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women', Clinical Infectious Diseases, vol. 52, no. 10, pp. 1248 - 1256. https://doi.org/10.1093/cid/cir119

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. / Kulkarni, Hemant; He, Weijing; Mlisana, Koleka; Wright, Edwina; Werner, Lise; Castiblanco, John; Dhanda, Rahul; Le, Tuan; Dolan, Mathew J; Guan, Weihua; Weiss, Robin A; Clark, Robert A; Abdool Karim, Salim S; Ahuja, Sunil K; Ndung'u, Thumbi.

In: Clinical Infectious Diseases, Vol. 52, No. 10, 2011, p. 1248 - 1256.

Research output: Contribution to journal › Article › Research › peer-review

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T1 - Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

AU - Kulkarni, Hemant

AU - He, Weijing

AU - Mlisana, Koleka

AU - Wright, Edwina

AU - Werner, Lise

AU - Castiblanco,, John

AU - Dhanda, Rahul

AU - Le, Tuan

AU - Dolan, Mathew J

AU - Guan, Weihua

AU - Weiss, Robin A

AU - Clark, Robert A

AU - Abdool Karim, Salim S

AU - Ahuja, Sunil K

AU - Ndung'u, Thumbi

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AB - The triangular relationship among pre-seroconversion PBC counts, host genotypes, and risk of HIV acquisition was determined in a prospective cohort of black South African high-risk female sex workers. Twentyseven women had seroconversion during follow-up, and 115 remained HIV negative for 2 years, despite engaging in high-risk activity

UR - http://cid.oxfordjournals.org/content/52/10/1248.full.pdf

U2 - 10.1093/cid/cir119

DO - 10.1093/cid/cir119

M3 - Article

VL - 52

SP - 1248

EP - 1256

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

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