Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

Hemant Kulkarni, Weijing He, Koleka Mlisana, Edwina Wright, Lise Werner, John Castiblanco,, Rahul Dhanda, Tuan Le, Mathew J Dolan, Weihua Guan, Robin A Weiss, Robert A Clark, Salim S Abdool Karim, Sunil K Ahuja, Thumbi Ndung'u

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Abstract

The triangular relationship among pre-seroconversion PBC counts, host genotypes, and risk of HIV acquisition was determined in a prospective cohort of black South African high-risk female sex workers. Twentyseven women had seroconversion during follow-up, and 115 remained HIV negative for 2 years, despite engaging in high-risk activity
Original languageEnglish
Pages (from-to)1248 - 1256
Number of pages9
JournalClinical Infectious Diseases
Volume52
Issue number10
DOIs
Publication statusPublished - 2011
Externally publishedYes

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